alpha1-antitrypsin

alpha1-antitrypsin
al·pha1-an·ti·tryp·sin (alґfə an″tĭ-tripґsin) 1. a plasma protein of the serpin group, an α1-globulin with Mr of 53,000, produced primarily in the liver; it is an acute phase reactant and inhibits the activity of elastase, cathepsin G, trypsin, and other proteolytic enzymes. Deficiency of this protein is associated with development of emphysema. Also written α1-antitrypsin. Called also alpha1-protease or proteinase inhibitor. 2. alpha1-proteinase inhibitor (human).

Medical dictionary. 2011.

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  • alpha1-antitrypsin deficiency panniculitis — a type of relapsing febrile nodular nonsuppurative panniculitis seen in persons with alpha1 antitrypsin deficiency; there are often painful subcutaneous nodules or plaques that may ulcerate …   Medical dictionary

  • alpha1-protease inhibitor — alpha1 proteinase inhibitor 1. alpha1 antitrypsin. 2. alpha1 proteinase inhibitor (human) …   Medical dictionary

  • alpha1-proteinase inhibitor (human) — a sterile, stable, lyophilized preparation of human alpha1 proteinase inhibitor (alpha1 antitrypsin) obtained from the pooled plasma of normal human donors; used in the treatment of congenital alpha1 antitrypsin deficiency …   Medical dictionary

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  • Alpha 1-antitrypsin — or α1 antitrypsin (A1AT) is a glycoprotein and generally known as serum trypsin inhibitor. The correct name, however, is alpha 1 proteinase inhibitor (A1PI) because it is a serine protease inhibitor (serpin) inhibiting a wide variety of proteases …   Wikipedia

  • Alpha-1-Antitrypsin-Mangel — Klassifikation nach ICD 10 E88.0 Störungen des Plasmaprotein Stoffwechsels, anderenorts nicht klassifiziert …   Deutsch Wikipedia

  • Alpha 1-antitrypsin deficiency — DiseaseDisorder infobox Name = Alpha 1 antitrypsin deficiency ICD10 = ICD10|E|88|0|e|70 ICD9 = ICD9|273.4 Caption = Structure of Alpha 1 antitrypsin Width = 150 ICDO = OMIM = 107400 DiseasesDB = 434 MedlinePlus = 000120 eMedicineSubj = med… …   Wikipedia

  • α1-antitrypsin — α1 an·ti·tryp·sin (an″tĭ tripґsin) alpha1 antitrypsin …   Medical dictionary

  • α-1-Antitrypsin — Bänder /Oberflächenmodell des Monomer nach PDB  …   Deutsch Wikipedia

  • α1-AT — alpha1 antitrypsin …   Medical dictionary

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