Blast phase

Blast phase
: Refers to advanced chronic myelogenous leukemia. In this phase, the number of immature, abnormal white blood cells in the bone marrow and blood is extremely high. Also called blast crisis.

Medical dictionary. 2011.

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  • blast crisis — A phase of chronic myelogenous leukemia in which tiredness, fever, and an enlarged spleen occur during the blastic phase, when more than 30% of the cells in the blood or bone marrow are blast cells (immature blood cells) …   English dictionary of cancer terms

  • blast transformation — The morphological and biochemical changes in B and T lymphocytes on exposure to antigen or to a mitogen. The cells appear to move from G0 to G1 stage of the cell cycle. They usually enlarge and proceed to S phase and mitosis later. The process… …   Dictionary of molecular biology

  • Leukemia, accelerated phase of — Refers to chronic myelogenous leukemia (CML) that is progressing. The number of immature, abnormal white blood cells in the bone marrow and blood is higher than in the chronic phase but not as high as in the blast phase …   Medical dictionary

  • Chronic phase — Refers to the early stages of chronic myelogenous leukemia. The number of immature, abnormal white blood cells in the bone marrow and blood is higher than normal, but lower than in the accelerated or blast phase …   Medical dictionary

  • chronic phase — Refers to the early stages of chronic myelogenous leukemia or chronic lymphocytic leukemia. The number of mature and immature abnormal white blood cells in the bone marrow and blood is higher than normal, but lower than in the accelerated or… …   English dictionary of cancer terms

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  • Blastic phase chronic myelogenous leukemia — is a phase of chronic myelogenous leukemia in which more than 30% of the cells in the blood or bone marrow are blast cells (immature blood cells). When tiredness, fever, and an enlarged spleen occur during the blastic phase, it is called blast… …   Wikipedia

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