aggrecan
Candidate gene for otosclerosis located at 15q25 to q26.

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ag·gre·can (agґrə-kan) the major structural proteoglycan of cartilage, consisting of a 210-kD core protein to which are linked about 100 chondroitin sulfate and a number of keratan sulfate and oligosaccharide chains; it binds to a link protein and to hyaluronan, creating large aggregates.

Medical dictionary. 2011.

Look at other dictionaries:

  • Aggrecan — Aggrecan, or large aggregating proteoglycan, is a proteoglycan, or a protein modified with carbohydrates; the human form of the protein is 2316 amino acids long and can be expressed in multiple isoforms due to alternative splicing.cite journal |… …   Wikipedia

  • Aggrecan — Masse/Länge Primärstruktur 2023 Aminosäuren …   Deutsch Wikipedia

  • aggrecan — The major structural proteoglycan of cartilage. It is a very large and complex macromolecule, comprising a core protein of 210 kD to which are linked around 100 chondroitin sulphate chains and several keratan sulphate chains as well as O and N… …   Dictionary of molecular biology

  • aggrecan — noun A proteoglycan, containing chondroitin sulfate, that is a major component of cartilage …   Wiktionary

  • ADAMTS4 — ADAM metallopeptidase with thrombospondin type 1 motif, 4, also known as ADAMTS4, is a human gene. PBB Summary section title = summary text = This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin… …   Wikipedia

  • MMP19 — Matrix metallopeptidase 19, also known as MMP19, is a human gene.cite web | title = Entrez Gene: MMP19 matrix metallopeptidase 19| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=4327| accessdate = ] PBB… …   Wikipedia

  • Aggrecanase — Aggrecanases are proteolytic enzymes that are members of the ADAM protein (A Disintegrin And Metalloprotease) family. Aggrecanases act on large proteoglycans known as aggrecans, which are components of connective tissues such as cartilage. The… …   Wikipedia

  • Ankylosierende Spondylarthritis — Klassifikation nach ICD 10 M45 Spondylitis ankylosans …   Deutsch Wikipedia

  • Ankylosierende Spondylitis — Klassifikation nach ICD 10 M45 Spondylitis ankylosans …   Deutsch Wikipedia

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