extractable nuclear antigens

extractable nuclear antigens
ENA; protein antigens, not containing DNA, that are extractable from cell nuclei in phosphate-buffered saline; anti-ENA antibodies are a component of the antinuclear antibodies occurring in systemic lupus erythematosus and other connective tissue diseases.

Medical dictionary. 2011.

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  • Extractable nuclear antigens — are soluble cytoplasmic and nuclear components that are antibody targets with over 100 different antigens described. The main 6 used in immunological laboratories for detection are Ro, La, Sm, RNP, Scl 70 and Jo1, which are screened for by… …   Wikipedia

  • Anti-nuclear antibody — Anti nuclear antibodies (ANAs, also known as anti nuclear factor or ANF ) are antibodies directed against contents of the cell nucleus. [MeshName|Antinuclear+Antibody] They are present in higher than normal numbers in autoimmune disease. The ANA… …   Wikipedia

  • Ouchterlony double immuno diffusion — (or agar gel immunodiffusion) is a simple, rather dated method which is still considered to be the gold standard for detection of ENAs (Extractable Nuclear Antigens).A gel plate is cut to form a series of holes in the gel (The geometry is… …   Wikipedia

  • Ouchterlony double immunodiffusion — Picture of an Ouchterlony double immunodiffusion plate, after immunodiffusion has taken place. In this, titre value of an antigen is quantified. The central well has an antibody, and the surrounding wells have decreasing concentration of the… …   Wikipedia

  • Mixed connective tissue disease — A mixture of three diseases of connective tissue (the framework of the cells of the body) systemic lupus erythematosus, scleroderma, and polymyositis. Patients with mixed connective tissue disease typically have features of each of the three… …   Medical dictionary

  • Ena — or ENA may refer to:Organizations* École nationale d administration, a school where many of France s senior officials are instructed * Energy Networks Association, a trade association representing natural gas and electricity companies in the… …   Wikipedia

  • ENA — Die Abkürzung ENA steht für: École nationale d’administration, die französische Elitehochschule European NAvigator, eine digitale Bibliothek zur Geschichte der Europäischen Einigung Escuela Nacional de Agricultura, Mexiko Escuela Nacional de… …   Deutsch Wikipedia

  • Ena — Die Abkürzung ENA steht für: École nationale d’administration, die französische Elitehochschule European NAvigator, eine digitale Bibliothek zur Geschichte der Europäischen Einigung Escuela Nacional de Agricultura, Mexiko Escuela Nacional de… …   Deutsch Wikipedia

  • Multiple Sklerose — Klassifikation nach ICD 10 G35 Multiple Sklerose (Encephalomyelitis disseminata) …   Deutsch Wikipedia

  • RNP antigen — [ribonucleoprotein] one of the extractable nuclear antigens …   Medical dictionary

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