alanine aminotransferase

alanine aminotransferase
An enzyme transferring amino groups from l-alanine to 2-ketoglutarate, or the reverse (from l-glutamate to pyruvate); there is a d-alanine transaminase that effects the same reaction, but using d-alanine and d-glutamate. Serum concentration is increased in viral hepatitis and myocardial infarction. SYN: alanine transaminase, glutamic-pyruvic transaminase, serum glutamic-pyruvic transaminase.

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alanine aminotransferase n an enzyme which promotes transfer of an amino group from glutamic acid to pyruvic acid and which when present in abnormally high levels in the blood is a diagnostic indication of liver disease abbr. ALT called also glutamic pyruvic transaminase

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(ALT)
an enzyme involved in the transamination of amino acids. Measurement of ALT in the serum is of use in the diagnosis and study of acute liver disease. It was formerly called serum glutamic pyruvic transaminase (SGPT).

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al·a·nine ami·no·trans·fer·ase (alґə-nēn ə-me″no-transґfər-ās) alanine transaminase.

Medical dictionary. 2011.

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