alanine transaminase

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(ALT) al·a·nine trans·am·i·nase (ALT) (alґə-nēn trans-amґĭ-nās) [EC 2.6.1.2] an enzyme of the transferase class that catalyzes the reversible transfer of an amino group from alanine to α-ketoglutarate to form glutamate and pyruvate, with pyridoxal phosphate as a cofactor. The reaction transfers nitrogen for excretion or for incorporation into other compounds. The enzyme is found in serum and body tissues, especially in the liver. Serum enzyme activity (SGPT) is greatly increased in liver disease and also elevated in infectious mononucleosis. Called also alanine aminotransferase and glutamic-pyruvic transaminase (GPT).

Medical dictionary. 2011.

Look at other dictionaries:

  • Alanine transaminase — protein Name = glutamic pyruvate transaminase caption = width = HGNCid = 4552 Symbol = GPT AltSymbols = EntrezGene = 2875 OMIM = 138200 RefSeq = NM 005309 UniProt = P24298 PDB = ECnumber = 2.6.1.2 Chromosome = 8 Arm = q Band = 24.2… …   Wikipedia

  • Alanine transaminase — Alanine amino transférase L alanine amino transférase (ALAT ou ALT) est une enzyme (EC 2.6.1.2) faisant partie des transaminases dont l activité est mesurée en biologie clinique lors du bilan hépatique. Elle se trouve en quantité importante… …   Wikipédia en Français

  • β-alanine transaminase — β al·a·nine trans·am·i·nase (alґə nēn trans amґĭ nās) 1. β alanine–α ketoglutarate transaminase. 2. β alanine–pyruvate transaminase …   Medical dictionary

  • alanine aminotransferase — An enzyme transferring amino groups from l alanine to 2 ketoglutarate, or the reverse (from l glutamate to pyruvate); there is a d alanine transaminase that effects the same reaction, but using d alanine and d glutamate. Serum concentration is… …   Medical dictionary

  • Alanine-oxo-acid transaminase — In enzymology, an alanine oxo acid transaminase (EC number|2.6.1.12) is an enzyme that catalyzes the chemical reaction:L alanine + a 2 oxo acid ightleftharpoons pyruvate + an L amino acidThus, the two substrates of this enzyme are L alanine and 2 …   Wikipedia

  • Alanine Amino Transférase — L alanine amino transférase (ALAT ou ALT) est une enzyme (EC 2.6.1.2) faisant partie des transaminases dont l activité est mesurée en biologie clinique lors du bilan hépatique. Elle se trouve en quantité importante surtout dans le foie. Son… …   Wikipédia en Français

  • Alanine amino transferase — Alanine amino transférase L alanine amino transférase (ALAT ou ALT) est une enzyme (EC 2.6.1.2) faisant partie des transaminases dont l activité est mesurée en biologie clinique lors du bilan hépatique. Elle se trouve en quantité importante… …   Wikipédia en Français

  • Alanine-oxomalonate transaminase — In enzymology, an alanine oxomalonate transaminase (EC number|2.6.1.47) is an enzyme that catalyzes the chemical reaction:L alanine + oxomalonate ightleftharpoons pyruvate + aminomalonateThus, the two substrates of this enzyme are L alanine and… …   Wikipedia

  • Alanine-glyoxylate transaminase — In enzymology, an alanine glyoxylate transaminase (EC number|2.6.1.44) is an enzyme that catalyzes the chemical reaction:L alanine + glyoxylate ightleftharpoons pyruvate + glycineThus, the two substrates of this enzyme are L alanine and… …   Wikipedia

  • Alanine amino transférase — Pour les articles homonymes, voir TGP. L alanine amino transférase (ALAT ou ALT) est une enzyme (EC 2.6.1.2) faisant partie des transaminases dont l activité est mesurée en biologie clinique lors du bilan hépatique. Elle se trouve en quantité… …   Wikipédia en Français

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