EAC rosette assay

EAC rosette assay
an assay for human B lymphocytes using complement receptors, a B cell marker. Peripheral blood cells are mixed with ox red blood cells, IgM antierythrocyte antibody, and complement deficient in C5 (to prevent red cell lysis). The antibody-and-complement-coated erythrocytes (EAC) form rosettes with B cells, which are counted using a hemocytometer.

Medical dictionary. 2011.

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Look at other dictionaries:

  • EAC rosette — see under assay …   Medical dictionary

  • Assay — An assay is an analysis done to determine: {{}}The presence of a substance and the amount of that substance. Thus, an assay may be done for example to determine the level of thyroid hormones in the blood of a person suspected of being hypothyroid …   Medical dictionary

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