hypothalamic-pituitary-adrenal axis

hypothalamic-pituitary-adrenal axis
the interrelationships between the endocrine structures and functions of the hypothalamus and adenohypophysis (the hypothalamic-pituitary axis) and the adrenal cortex, including production of corticotropin, its reception at sites in the adrenal cortex, and negative feedback mechanisms by which high levels of circulating glucocorticoids such as cortisol act on the hypothalamus and adenohypophysis to inhibit secretion of corticotropin. Called also HPA a. and hypothalamus-pituitary-adrenal a.

Medical dictionary. 2011.

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  • Hypothalamic-pituitary-adrenal axis — The hypothalamic pituitary adrenal axis (HPA or HTPA axis), also known as the limbic hypothalamic pituitary adrenal axis (LHPA axis), is a complex set of direct influences and feedback interactions among the hypothalamus (a hollow, funnel shaped… …   Wikipedia

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  • Adrenal cortex — Layers of cortex. Latin cortex glandulae suprarenalis Gray s …   Wikipedia

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