hypothalamic-pituitary-gonadal axis

hypothalamic-pituitary-gonadal axis
the interrelationships between the hypothalamic-pituitary axis and the gonads, including production of gonadotropins, their reception at sites in the testis or ovary, and negative feedback mechanisms by which high levels of circulating estrogens or androgens act on the hypothalamus and adenohypophysis to inhibit secretion of gonadotropins. It is sometimes called the hypothalamic-pituitary-testicular axis in males and the hypothalamic-pituitary-ovarian axis in females. Called also HPG a. and hypothalamus-pituitary-gonad a.

Medical dictionary. 2011.

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