Acquired mutation
A change in a gene or chromosome that occurs in a single cell after the conception of the individual. That change is then transmitted to all cells descended from that cell, giving rise to a clone of cells marked by the mutation. Acquired mutations occur in the general body cells, as opposed to the germ cells, and so are not transmitted to the children. Some acquired mutations are involved in the development of cancer. Also called a somatic mutation.

Medical dictionary. 2011.

Look at other dictionaries:

  • Mutation, acquired — A change in a gene or chromosome that occurs in a single cell after the conception of the individual. That change is then transmitted to all cells descended from that cell, giving rise to a clone of cells marked by the mutation. Acquired… …   Medical dictionary

  • Mutation — A permanent change, a structural alteration, in the DNA or RNA. In humans and many other organisms, mutations occur in DNA. However, in retroviruses like HIV, mutations occur in RNA which is the genetic material of retroviruses. In most cases,… …   Medical dictionary

  • Acquired — Anything that is not present at birth but develops some time later. In medicine, the word acquired implies new or added. An acquired condition is new in the sense that it is not genetic (inherited) and added in the sense that was not present at… …   Medical dictionary

  • Mutation — For other uses, see Mutation (disambiguation). Part of the Biology series on Evolution …   Wikipedia

  • Mutation, germline — A heritable change in the DNA that occurred in a germ cell (a cell destined to become an egg or in the sperm) or the zygote (the conceptus) at the single cell stage. When transmitted to a child, a germline mutation is incorporated in every cell… …   Medical dictionary

  • Mutation, somatic — A change in a gene or chromosome that occurs in a general body cell, as opposed to a germ cell, and so cannot be transmitted to children. A somatic mutation occurs in a single cell after the conception of the individual. That change is then… …   Medical dictionary

  • JAK2-Mutation — Die JAK2 V617F Punktmutation ist eine genetische Mutation, die ein wichtiger neuer Marker für die Diagnose der chronische myeloproliferative Erkrankungen oder myeloproliferative Syndrome (häufig MPS abgekürzt) ist, einer Gruppe von Krankheiten,… …   Deutsch Wikipedia

  • Adaptive mutation — Evolutionary theory describes that mutagenesis occurs randomly, regardless of the utility of a genetic mutation to the organism. If it is beneficial or neutral, the organism will survive to reproduce and pass on the mutation. However, molecular… …   Wikipedia

  • Germline mutation — A germline mutation is any detectable and heritable variation in the lineage of germ cells. Mutations in these cells are transmitted to offspring, while, on the other hand, those in somatic cells are not. A germline mutation gives rise to a… …   Wikipedia

  • Somatic mutation — A change in a gene or chromosome that occurs in a general body cell, as opposed to a germ cell, and so cannot be transmitted to children. A somatic mutation occurs in a single cell after the conception of the individual. That change is then… …   Medical dictionary

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