amphotericin, amphotericin B
C46H73NO20; an amphoteric polyene antibiotic prepared from Streptomyces nodosus and available as the sodium deoxycholate complex; also a nephrotoxic antifungal agent used extensively in the treatment of systemic mycoses.

Medical dictionary. 2011.

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  • amphotericin B — amphotericin amphotericin, amphotericin B amphotericin B . 1. an antibiotic and antifungal agent ({C47H73NO17}), produced by a strain of {Streptomyces nodosus}. It is one of a class of polyene macrolide antibiotics effective against fungal… …   The Collaborative International Dictionary of English

  • amphotericin — amphotericin, amphotericin B amphotericin B . 1. an antibiotic and antifungal agent ({C47H73NO17}), produced by a strain of {Streptomyces nodosus}. It is one of a class of polyene macrolide antibiotics effective against fungal infections. It has… …   The Collaborative International Dictionary of English

  • Amphotericin B — Systematic (IUPAC) name (1R,3S,5R,6R,9 …   Wikipedia

  • amphotericin B — n the amphotericin that is clinically useful against deep seated and systemic fungal infections * * * am·pho·ter·i·cin B (am″fə terґĭ sin) [USP] one of two polyene antifungal antibiotics (the other, amphotericin A, is not used… …   Medical dictionary

  • amphotericin B cholesteryl complex — amphotericin B complexed with cholesteryl sulfate in a 1:1 ratio; administered by intravenous infusion in the treatment of disseminated aspergillosis in patients refractory to or intolerant of conventional amphotericin B therapy …   Medical dictionary

  • amphotericin B lipid complex — amphotericin B complexed with two phospholipids in a 1:1 drug to lipid ratio; administered by intravenous infusion in the treatment of invasive fungal infections in patients who are refractory to or intolerant of conventional amphotericin B… …   Medical dictionary

  • amphotericin B liposomal complex — amphotericin B intercalated into a single bilayer liposome; administered by intravenous infusion in the treatment of severe systemic fungal infections and visceral leishmaniasis in patients refractory to or intolerant of conventional amphotericin …   Medical dictionary

  • amphotericin B — [am΄fə ter′ə sin] n. 〚 AMPHOTERIC + IN1〛 an antibiotic compound, C46H73NO20, used in treating certain diseases caused by parasitic fungi, such as systemic candidiasis * * * …   Universalium

  • amphotericin B — [am΄fə ter′ə sin] n. [ AMPHOTERIC + IN1] an antibiotic compound, C46H73NO20, used in treating certain diseases caused by parasitic fungi, such as systemic candidiasis …   English World dictionary

  • Amphotericin B — Strukturformel Allgemeines Freiname Amphotericin B Andere Namen …   Deutsch Wikipedia

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