- Arrest of maturation of leukocytes in their production centers, thereby resulting in greater numbers of young forms and progressively smaller proportions of mature granular cells in the bone marrow, as observed in agranulocytosis. [G. an- priv. + akmenos, full grown, fr. akme, highest point]
* * *an·ak·me·sis (an-akґme-sis) [an-1 + Gr. akmēnos full grown] arrest of maturation; specifically, increase of granulocyte precursors in the marrow with lack of further maturation, as seen in agranulocytosis.
Medical dictionary. 2011.