second-generation cephalosporin

second-generation cephalosporin
any of a group containing cephalosporins that have greater resistance to β-lactamases and so are more active against gram-negative organisms, but are slightly less active against gram-positive organisms than are first-generation agents; it includes cefaclor, cefamandole, cefonicid, cefotetan, cefoxitin, cefprozil, ceftibuten, and cefuroxime. Cephamycins are usually classified as second-generation cephalosporins but have somewhat greater activity against anaerobes.

Medical dictionary. 2011.

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  • third-generation cephalosporin — any of a group of β lactamase–resistant cephalosporins that are more active against gram negative organisms but less active against gram positive organisms than are second generation agents; it includes cefixime, cefoperazone, cefotaxime,… …   Medical dictionary

  • Cephalosporin — See also: Discovery and development of cephalosporins Core structure of the cephalosporins …   Wikipedia

  • cephalosporin — /sef euh loh spawr in, spohr /, n. Pharm. any of a group of widely used broad spectrum antibiotics, originally isolated as a product of fermentation from the fungus Cephalosporium acremonium. [1950 55; < NL Cephalospor(ium) the genus (see CEPHALO …   Universalium

  • cephalosporin — n. any one of a group of semisynthetic beta lactam antibiotics, derived from the mould Cephalosporium, which are effective against a wide range of microorganisms and are therefore used in a variety of infections. The older (first generation)… …   The new mediacal dictionary

  • Cefuroxime — Systematic (IUPAC) name (6R,7R) 3 {[(aminocarbonyl)oxy]methyl} 7 {[(2Z) 2 (2 furyl) 2 (methoxyimino) acetyl]amino} 8 oxo 5 thia 1 azabicyclo[4.2.0]oct 2 ene 2 carboxylic acid …   Wikipedia

  • Cefaclor — Systematic (IUPAC) name (6R,7R) 7 {[(2R) 2 amino 2 phenylacetyl]amino} 3 chloro 8 oxo 5 thia 1 azabicyclo[4.2.0]oct 2 ene 2 carboxylic acid Clinical data …   Wikipedia

  • Cefprozil — Systematic (IUPAC) name 7 [2 amino 2 (4 hydroxyphenyl) acetyl]amino 8 oxo 3 prop 1 enyl 5 thia 1 azabicyclo[4.2.0]oct 2 ene 2 carboxylic acid Clinical data Trade na …   Wikipedia

  • cefaclor — A semisynthetic broad spectrum antibiotic derived from cephalosporin C; used orally. * * * cef·a·clor sef ə klȯr, klōr n a semisynthetic cephalosporin antibiotic C15H14ClN3O4S·H2O that is administered orally to treat a wide range of bacterial… …   Medical dictionary

  • Cefotiam — Systematic (IUPAC) name (6R,7R) 7 {[2 (2 amino 1,3 thiazol 4 yl)acetyl] amino} 3 {[1 (2 dimethylaminoethyl)tetrazol 5 yl] sulfanylmethyl} 8 oxo 5 thia 1 azabicyclo[4.2.0] oct 2 ene 2 carboxylic acid …   Wikipedia

  • ceforanide — A broad spectrum long acting cephalosporin antibiotic. * * * ce·for·a·nide (sə forґə nīd) [USP] a semisynthetic second generation cephalosporin with actions and uses similar to those of cefamandole; administered intramuscularly or… …   Medical dictionary

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