cysteine endopeptidase

cysteine endopeptidase
cys·te·ine en·do·pep·ti·dase (sisґte-ēn en″do-pepґtĭ-dās) [EC 3.4.22] any of a group of endopeptidases containing at the active site a cysteine residue involved in catalysis; the group includes papain and several cathepsins. Called also thiol endopeptidase.

Medical dictionary. 2011.

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  • Cysteine protease — Cysteine Peptidase Crystal structure of the cysteine peptidase papain in complex with its covalent inhibtor E 64. Rendered from PDB 1PE6 Identifiers …   Wikipedia

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  • endopeptidase — An enzyme catalyzing the hydrolysis of a peptide chain at points well within the chain, not near termini; e.g., pepsin, trypsin. Cf.:exopeptidase. SYN: proteinase. * * * en·do·pep·ti·dase pep tə .dās, .dāz n any of a group of enzymes that… …   Medical dictionary

  • thiol endopeptidase — thi·ol en·do·pep·ti·dase (thiґol en″do pepґtĭ dās) cysteine endopeptidase …   Medical dictionary

  • chymopapain — A cysteine proteinase similar to papain in specificity; on rare occasions, it is used to shrink slipped disks as an alternative to surgery; used as a meat tenderizer. It is the major endopeptidase of papaya. * * * chy·mo·pa·pa·in .kī mō pə pā ən …   Medical dictionary

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  • Ficain — (or ficin) is an enzyme which is derived from figs latex. It is of a family of proteases known as the cysteine endopeptidases, a group that also includes papain derived from papaya latex, bromelase (bromelain) extracted from pineapple stem,… …   Wikipedia

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  • ficain — SYN: ficin (2). * * * fi·cain (fiґkān) [EC 3.4.22.3] an enzyme of the hydrolase class that catalyzes the cleavage of proteins on the carboxyl side of lysine, alanine, tyrosine, glycine, asparagine, leucine, and valine bonds. It is a cysteine …   Medical dictionary

  • ficin — 1. A cysteine endopeptidase isolated from figs (Ficus carica, globata, and doliaria); used in industry as a protein digestant; f. has a wide specificity for protein substrates; an anthelmintic. 2. The crude dried latex from Ficus spp. SYN: ficain …   Medical dictionary

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