Brushfield’s spots
Speckled iris. Little white spots that slightly elevated on the surface of the iris arranged in a ring concentric with the pupil. These spots occur in normal children but are far more frequent in Down’s syndrome (trisomy 21). They were described in 1924 by Thomas Brushfield and are due to aggregation of a normal iris element (connective tissue).

Medical dictionary. 2011.

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  • Spots, Brushfield’s — Speckled iris. Little white spots that slightly elevated on the surface of the iris and are arranged in a ring concentric with the pupil. These spots occur in normal children but are far more frequent in Down’s syndrome (trisomy 21). They were… …   Medical dictionary

  • Brushfield spots — greyish brown spots seen in the iris of the eye. They can be found in normal individuals but are usually associated with Down s syndrome. T. Brushfield (1858 1937), British physician * * * Brush·field spots (brushґfēld) [Thomas Brushfield,… …   Medical dictionary

  • Brushfield spots — greyish brown spots seen in the iris of the eye. They can be found in normal individuals but are usually associated with Down s syndrome. [Brushfield (1858–1937), British physician] …   The new mediacal dictionary

  • Синдром Дауна (Down'S Syndrome) — заболевание, возникающее в результате генетической аномалии, при которой в организме человека появляется дополнительная хромосома (вместо двух хромосом 21 присутствует три); в результате общее количество хромосом становится равным 47. тогда как в …   Медицинские термины

  • Dalrymple's sign — is a widened palpebral (eyelid) opening, or eyelid spasm, seen in thyrotoxicosis (as seen in Graves disease, exophthalmic Goitre and other hyperthyroid conditions), causing abnormal wideness of the palpebral fissure. As a result of the retraction …   Wikipedia

  • Down's syndrome — a condition resulting from a genetic abnormality in which an extra chromosome is present (there are three no. 21 chromosomes instead of the usual two), giving a total of 47 chromosomes rather than the normal 46. The chances of having a Down s… …   Medical dictionary

  • Down's syndrome — Down syndrome a condition resulting from a chromosomal abnormality most commonly due to the presence of three copies of chromosome 21 (trisomy 21), which is most likely to occur with advanced maternal age. Down s syndrome can also occur as a… …   The new mediacal dictionary

  • Down syndrome — Classification and external resources Boy with Down syndrome assembling a …   Wikipedia

  • Iris, speckled — Due to little white (or lightly colored) spots that are slightly elevated on the surface of the iris. These spots, arranged in a ring concentric with the pupil, occur in normal children but are far more frequent in Down’s syndrome (trisomy 21).… …   Medical dictionary

  • Speckled iris — Due to little white (or lightly colored) spots that are slightly elevated on the surface of the iris. These spots, arranged in a ring concentric with the pupil, occur in normal children but are far more frequent in Down’s syndrome (trisomy 21).… …   Medical dictionary

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