dUTP pyrophosphatase

dUTP pyrophosphatase
dUTP py·ro·phos·pha·tase (pi-ro-fosґfə-tās) [EC 3.6.1.23] an enzyme of the hydrolase class that catalyzes the cleavage of dUTP to form dUMP and pyrophosphate. It thus both reduces dUTP levels and also provides dUMP as a substrate dTTP biosynthesis, decreasing the intracellular concentration dUPT and so preventing incorporation of uracil into DNA; it is critical for the fidelity of DNA replication and repair. In official nomenclature, the preferred name is now dUTP diphosphatase.

Medical dictionary. 2011.

Игры ⚽ Поможем написать курсовую

Look at other dictionaries:

  • dUTP diphosphatase — Identifiers EC number 3.6.1.23 CAS number 37289 34 2 …   Wikipedia

  • DUTP diphosphatase — In enzymology, a dUTP diphosphatase (EC number|3.6.1.23) is an enzyme that catalyzes the chemical reaction:dUTP + H2O ightleftharpoons dUMP + diphosphateThus, the two substrates of this enzyme are dUTP and H2O, whereas its two products are dUMP… …   Wikipedia

  • DUT (gene) — Deoxyuridine triphosphatase PDB rendering based on 1q5h …   Wikipedia

  • DUT — is an acronym for Dalian University of Technology in Dalian, China Delft University of Technology in Delft, the Netherlands Da Nang University of Technology in Da Nang, Viet Nam Durban University of Technology in Durban, South Africa Device under …   Wikipedia

  • Gp120 — Position de la Gp120 sur le VIH La GP120 est une glycoprotéine exprimée par le VIH (virus responsable du syndrome d immunodéficience acquise ou SIDA) Sommaire 1 Origine …   Wikipédia en Français

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”