plasma cell dyscrasias

plasma cell dyscrasias
a diverse group of neoplastic diseases involving proliferation of a single clone of cells producing a serum M component (a monoclonal immunoglobulin or immunoglobulin fragment); the cells usually have plasma cell morphology, but may have lymphocyte morphology or a combination of lymphocytic and plasma cellular. The group includes multiple myeloma, Waldenstrцm macroglobulinemia, the heavy chain diseases, and benign monoclonal gammopathy. Called also dysproteinemias, monoclonal gammopathies or immunoglobulinopathies, and paraproteinemias.

Medical dictionary. 2011.

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  • Plasma cell dyscrasia — ICD9 = ICDO = 9730 9739 OMIM = MedlinePlus = eMedicineSubj = eMedicineTopic = MeshID = D054219 Plasma cell dyscrasias are disorders of the plasma cells; they include malignant and non malignant disorders. Malignant disorders are termed plasma… …   Wikipedia

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  • Multiple myeloma — Classification and external resources Micrograph of a plasmacytoma, the histologic correlate of multiple myeloma. H E stain ICD …   Wikipedia

  • plasmacytoma — A discrete, presumably solitary mass of neoplastic plasma cells in bone or in one of various extramedullary sites; in humans, such lesions are probably the initial phase of developing plasma cell myeloma. [plasmacyte + G. oma …   Medical dictionary

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  • plasmacytoid lymphocyte — a cell morphologically resembling a small lymphocyte but having a well developed rough endoplasmic reticulum like that of a plasma cell; frequently observed in the blood of patients with plasma cell dyscrasias or hypergammaglobulinemia …   Medical dictionary

  • immunosecretory disorders — a group of disorders characterized by monoclonal proliferation of immunoglobulin producing cells that resemble lymphocytes or plasma cells; the group includes AL amyloidosis, cryoglobulinemia, heavy chain disease, benign monoclonal gammopathy,… …   Medical dictionary

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