Burkitt lymphoma
: A type of non-Hodgkin lymphoma (NHL) that most often occurs in young people between the ages of 12 and 30, accounting for 40% to 50% of childhood NHL. The disease usually causes a rapidly growing tumor in the abdomen. Up to 90% of these tumors are in the abdomen. Other sites of involvement include the testis, sinuses, bone, lymph nodes, skin, bone marrow, and central nervous system. Burkitt lymphoma is a small noncleaved cell lymphoma of B-cell origin. About 25% of Burkitt lymphomas contain Epstein-Barr virus genomes. These tumors are due to a characteristic chromosomal translocation, usually a t(8;14) translocation or, less often, a t(8;22) or t(2;8) translocation. Each of these translocations juxtaposes the c-myc oncogene with immunoglobulin locus regulatory elements, resulting in the inappropriate expression of c-myc, a gene involved in cellular proliferation.

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Bur·kitt lymphoma (burґkit) [Denis Parsons Burkitt, Irish surgeon in Uganda, 1911–1993] see under lymphoma.

Medical dictionary. 2011.

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  • Burkitt lymphoma — Burkitt lymphoma. См. лимфома Беркитта. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Burkitt lymphoma — ▪ disease       a cancer of the lymphatic system that has an especially high incidence in equatorial Africa among children 3 to 16 years of age. The disease is characterized by tumours of the jaw bones and abdomen and is named after Denis Burkitt …   Universalium

  • Burkitt lymphoma — An aggressive (fast growing) type of B cell non Hodgkin lymphoma that occurs most often in children and young adults. The disease may affect the jaw, central nervous system, bowel, kidneys, ovaries, or other organs. There are three main types of… …   English dictionary of cancer terms

  • Burkitt lymphoma — noun see Burkitt s lymphoma …   New Collegiate Dictionary

  • burkitt lymphoma — noun see burkitt s lymphoma …   Useful english dictionary

  • Burkitt's lymphoma — Infobox Disease Name = Burkitt s lymphoma Caption = Burkitt lymphoma, touch prep, Wright stain DiseasesDB = 1784 ICD10 = ICD10|C|83|7|c|81 ICD9 = ICD9|200.2 ICDO = 9687/3 | OMIM = 113970 MedlinePlus = eMedicineSubj = med eMedicineTopic = 256… …   Wikipedia

  • Lymphoma — This article is about lymphoma in humans. For the disease in dogs, cats, and ferrets, see lymphoma in animals. Lymphoma Classification and external resources Follicular lymphoma replacing a lymph node …   Wikipedia

  • Burkitt, Denis Parsons — ▪ 1994       Irish physician (b. Feb. 28, 1911, Enniskillen, Northern Ireland d. March 23, 1993, England), recognized the significance of varying climatic conditions and eating habits in the incidence of cancer and certain other diseases. His… …   Universalium

  • Burkitt's lymphoma — Bur·kitt s lymphoma .bər kəts also Burkitt lymphoma kət n a malignant lymphoma that affects primarily the upper and lower jaws, orbit, retroperitoneal tissues situated near the pancreas, kidneys, ovaries, testes, thyroid, adrenal glands, heart,… …   Medical dictionary

  • Burkitt's lymphoma — also Burkitt lymphoma noun Etymology: Denis Parsons Burkitt died 1993 British surgeon Date: 1963 a malignant lymphoma that occurs especially in children of central Africa and is associated with Epstein Barr virus …   New Collegiate Dictionary

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