- Pneumoconiosis due to inhalation of asbestos fibers suspended in the ambient air; sometimes complicated by pleural mesothelioma or bronchogenic carcinoma; ferruginous bodies are the histologic hallmark of exposure to asbestos.
* * *as·bes·to·sis .as-.bes-'tō-səs, .az- n, pl -to·ses -.sēz a pneumoconiosis due to asbestos particles that is marked by fibrosis and scarring of lung tissue
* * *n.a lung disease - a form of pneumoconiosis - caused by fibres of asbestos inhaled by those who are exposed to the mineral. The incidence of lung cancer is high in such patients, particularly if they smoke cigarettes. See also mesothelioma.
* * *as·bes·to·sis (as″bes-toґsis) [asbestos + -osis] a form of pneumoconiosis (silicatosis) caused by inhaling fibers of asbestos, marked by interstitial fibrosis of the lung varying in extent from minor involvement of the basal areas to extensive scarring; it is associated with pleural mesothelioma and bronchogenic carcinoma.
Asbestosis specimen showing asbestos fibers (arrows) coated with iron to form ferruginous bodies. Alveolar walls demonstrate fibrotic thickening and parenchymal scarring (H & E stain). (Inset), Beaded ferruginous body within a macrophage (Prussian blue stain).
Medical dictionary. 2011.