glutathione synthetase

glutathione synthetase
glu·ta·thi·one syn·the·tase (gloo″tə-thiґōn sinґthə-tās) an enzyme of the ligase class that catalyzes the ATP-dependent formation of glutathione from glycine and γ-glutamylcysteine. In EC nomenclature, called glutathione synthase.

Medical dictionary. 2011.

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  • Glutathione synthetase — protein Name=glutathione synthetase caption= width= HGNCid=4624 Symbol=GSS AltSymbols= EntrezGene=2937 OMIM=601002 RefSeq=NM 000178 UniProt=P48637 PDB= ECnumber=6.3.2.3 Chromosome=20 Arm=q Band=11.2 LocusSupplementaryData=Glutathione synthetase… …   Wikipedia

  • Glutathione synthetase deficiency — Classification and external resources Glutathione OMIM 266130 …   Wikipedia

  • glutathione synthetase deficiency — glu·ta·thi·one syn·the·tase de·fi·cien·cy (gloo″tə thiґōn sinґthə tās) an autosomal recessive aminoacidopathy due to mutation in the GSS gene (locus: 20q11.2), which encodes glutathione synthetase, resulting in decreased …   Medical dictionary

  • Glutathione — Glutathione[1] …   Wikipedia

  • Glutathione synthase — In enzymology, a glutathione synthase (EC number|6.3.2.3) is an enzyme that catalyzes the chemical reaction:ATP + gamma L glutamyl L cysteine + glycine ightleftharpoons ADP + phosphate + glutathioneThe 3 substrates of this enzyme are ATP, gamma L …   Wikipedia

  • glutathione synthase — glu·ta·thi·one syn·thase (gloo″tə thiґōn sinґthās) [EC 6.3.2.3] official nomenclature for glutathione synthetase …   Medical dictionary

  • glutathione — A tripeptide of glycine, l cysteine, and l glutamate, with l glutamate having an isopeptide bond with the amino moiety of l cysteine. G. has a wide variety of roles in a cell; it is the most prevalent non protein thiol. G. disulfide (GSSG)… …   Medical dictionary

  • Gamma-glutamylcysteine synthetase — (EC 6.3.2.2) (glutamate cysteine ligase, GCL) is the first enzyme in the glutathione biosynthesis pathway. FunctionIt catalyses the ATP dependent condensation of cysteine and glutamate to form the dipeptide gamma glutamylcysteine. The peptide… …   Wikipedia

  • γ-glutamylcysteine synthetase deficiency — γ glu·ta·myl·cys·te·ine syn·the·tase de·fi·cien·cy (gloo″tə məl sisґte ēn sinґthə tās) an autosomal recessive aminoacidopathy of glutathione synthesis caused by mutation in the GCLC gene (locus: 6p12), which… …   Medical dictionary

  • GCLC — Glutamatcysteinligase (Brassica juncea) Strukturmodell der Glutamatcysteinligase aus dem …   Deutsch Wikipedia

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