type IV hypersensitivity

type IV hypersensitivity
hypersensitivity initiated by antigen-specific T lymphocytes; unlike forms mediated by antibodies, it takes one or more days to develop and can be transferred by lymphocytes but not by serum. The term is often equated with delayed hypersensitivity, although the latter is sometimes restricted to hypersensitivity involving cytokine-mediated reactions (as contrasted with direct cytolysis). See type IV hypersensitivity reaction, under hypersensitivity reaction, at reaction. Called also cell- or T cell–mediated h.

Medical dictionary. 2011.

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