Catecholamine
Pronounced cat·e·chol·amine. An amine derived from the amino acid tyrosine — examples include epinephrine (adrenaline), norepinephrine (noradrenaline), and dopamine — that act as hormones or neurotransmitters. There are a number of disorders involving catecholamines, including neuroblastoma, pheochromocytoma, chemodectina, the familial paraganglioma syndrome, dopamine-ß-hydroxalase deficiency, and tetrahydrobiopterin deficiency Neuroblastoma is the second most common solid tumor in childhood (after brain tumors). It usually produce catecholamines. The catecholamine metabolites vanillylmandelic acid and homovanillic acid can be measured quantitatively in the urine as a test for the disease. Pheochromocytoma is a benign tumor derived from the adrenal medulla or sympathetic paraganglia. The tumor secretes epinephrine and norepinephrine. These catecholamines cause attacks of hypertension, headache, nausea and vomiting, sweating, pallor and severe apprehension. Chemodectoma is another benign tumor of the chemoreceptor system, the most common types being the carotid body tumor and the glomus jugulare tumor. Also known as nonchromaffin paraganglioma. Familial paraganglioma syndrome is an unusual familial disease involving slow-growing benign tumors — paragangliomas, glomus tumors, or chemodectomas — predominantly in the head and neck region. The gene for the disease is on chromosome 11q23. The tumors may lead to disfiguring local swellings, cranial nerve injury, or involvement of the base of the skull and may cause dysphonia, aspiration, hearing loss, dysphagia, tinnitus, pain, persistent cough, and shoulder weakness (due to tumor encroachment on cranial nerves). All individuals with hereditary paragangliomas inherit the disease gene from their father. This is consistent with genomic imprinting: the maternally derived gene is inactivated during oogenesis and can be reactivated only during spermatogenesis.

* * *

cat·e·chol·amine .kat-ə-'kō-lə-.mēn, -'kȯ- n any of various amines (as epinephrine, norepinephrine, and dopamine) that contain a dihydroxy benzene ring, that are derived from tyrosine, and that function as hormones or neurotransmitters or both

* * *

cat·e·chol·amine (kat″ə-kolґə-mēn) one of a group of biogenic amines having a sympathomimetic action, the aromatic portion of whose molecule is catechol, and the aliphatic portion an amine; examples are dopamine, norepinephrine, and epinephrine.

Medical dictionary. 2011.

Look at other dictionaries:

  • catécholamine — [ katekɔlamin ] n. f. • 1958; de catéchol et amine ♦ Physiol. Substance du groupe des amines sécrétée par la médullosurrénale, affectant le système nerveux sympathique et jouant un rôle de neurotransmetteur. L adrénaline, la noradrénaline et la… …   Encyclopédie Universelle

  • Catecholamine — Catécholamine Les catécholamines sont des composés organiques synthétisés à partir de la tyrosine et jouant le rôle d hormone ou de neurotransmetteur. Les catécholamines les plus courantes sont l adrénaline (épinéphrine), la noradrénaline… …   Wikipédia en Français

  • catecholamine — n. [catechol + amine.] any of a group of chemicals including epinephrine and norepinephrine that are produced in the medulla of the adrenal gland. They function as nerotransmitters in the sympathetic nervous system. Also, any structurally related …   The Collaborative International Dictionary of English

  • Catecholamine — Catecholamine, biogene Amine, deren Biosynthese im Organismus von der Aminosäure Tyrosin ausgeht und deren wichtigste Vertreter als vom Nebennierenmark produzierte und freigesetzte Hormone (⇒ Noradrenalin, ⇒ Adrenalin) und als von adrenergen… …   Deutsch wörterbuch der biologie

  • catecholamine — type of hormone, from catechol (1880), from catechu, an astringent substance used in medicines, dyeing, etc., which apparently is from Malay kachu …   Etymology dictionary

  • catecholamine — [kat΄ə chōl′ə mēn΄, kat΄ə chōl′əmin; kat΄əkōl′ə mēn΄] n. [ CATECHOL + AMINE] any of various compounds, as norepinephrine and dopamine, that are secretions, or byproducts of secretions, of the medulla of the adrenal gland and that affect the… …   English World dictionary

  • Catecholamine — Catechol dopamine …   Wikipedia

  • Catécholamine — Les catécholamines sont des composés organiques synthétisés à partir de la tyrosine et jouant le rôle d hormone ou de neurotransmetteur. Les catécholamines les plus courantes sont l adrénaline (épinéphrine), la noradrénaline (norépinéphrine) et… …   Wikipédia en Français

  • Catecholamine — Katecholamine, auch Catecholamine oder Brenzcatechinamine, sind eine Klasse von körpereigenen und künstlichen Stoffen, die an den sympathischen Alpha und Beta Rezeptoren des Herz Kreislaufsystems eine anregende Wirkung haben. Somit fungieren… …   Deutsch Wikipedia

  • catecholamine — /kat i kol euh meen , koh leuh /, n. Biochem. any of a group of chemically related neurotransmitters, as epinephrine and dopamine, that have similar effects on the sympathetic nervous system. [1950 55; CATECHOL + AMINE] * * * Any naturally… …   Universalium

  • catecholamine — noun Any of a class of aromatic amines derived from pyrocatechol that are hormones produced by the adrenal gland. Epinephrine and dopamine are two other catecholamine transmitters. See Also: catecholaminergic …   Wiktionary

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”