2,3-bisphosphoglycerate

2,3-bisphosphoglycerate
An intermediate in the Rapoport-Luebering shunt, formed between 1,3-bisphosphoglycerate and 3-phosphoglycerate; an important regulator of the affinity of hemoglobin for oxygen; an intermediate of phosphoglycerate mutase.
- b. mutase an enzyme of the Rapoport-Luebering shunt; it catalyzes the reversible interconversion of 1,3-bisphosphoglycerate to b.; it also has a phosphatase activity, converting b. to orthophosphate and 3-phosphoglycerate; a deficiency of b. mutase can result in mild erythrocytosis.

Medical dictionary. 2011.

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