CAD protein

CAD protein
a protein containing catalytic sites for three enzyme activities: carbamoyl-phosphate synthase (glutamine-hydrolyzing) [EC 6.3.5.5], aspartate carbamoyltransferase [EC 2.1.3.2], and dihydroorotase [EC 3.5.2.3]. The enzyme activities catalyze the first three reactions of pyrimidine biosynthesis.

Medical dictionary. 2011.

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  • dihydroorotase — di·hy·dro·or·o·tase (di hi″dro orґo tās) [EC 3.5.2.3] an enzyme activity of the trifunctional CAD protein (q.v.); it is a ligase that catalyzes the cyclization of carbamoylaspartate, creating the initial ring structure (dihydroorotate) …   Medical dictionary

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