serum amyloid A protein

serum amyloid A protein
a high-molecular-weight protein synthesized in the liver; it is an acute phase protein and circulates in association with a subclass of HDL lipoproteins. It is the precursor to AA amyloid and accumulates in inflammation. Called also SAA p.

Medical dictionary. 2011.

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  • Serum amyloid A — protein Name = Human Serum amyloid A1 caption = width = HGNCid = 10513 Symbol = SAA1 AltSymbols = EntrezGene = 6288 OMIM = 104750 RefSeq = NM 199161 UniProt = P02735 PDB = ECnumber = Chromosome = 11 Arm = p Band = 15.1 LocusSupplementaryData =… …   Wikipedia

  • Serum amyloid P component — Amyloid P component, serum (SAP) is the identical serum form of amyloid P component (AP), a 25kDa pentameric protein first identified as the pentagonal constituent of in vivo pathological deposits called amyloid .cite journal | author = Cathcart… …   Wikipedia

  • serum amyloid — In secondary amyloidosis the fibrils deposited in tissues are unrelated to immunoglobulin light chains (in contrast to the situation in primary amyloidosis) and are made of amyloid A protein (AA protein). This is derived from serum amyloid A… …   Dictionary of molecular biology

  • Protein — A large molecule composed of one or more chains of amino acids in a specific order determined by the base sequence of nucleotides in the DNA coding for the protein. Proteins are required for the structure, function, and regulation of the body s… …   Medical dictionary

  • Amyloid — Amyloids are insoluble fibrous protein aggregates sharing specific structural traits. Abnormal accumulation of amyloid in organs may lead to amyloidosis, and may play a role in various other neurodegenerative diseases. Definition controversyThe… …   Wikipedia

  • amyloid — Glycoprotein deposited extracellularly in tissues in amyloidosis. The glycoprotein may either derive from light chain of immunoglobulin (AIO (amyloid of immune origin): 5 18 kD glycoprotein; product of a single clone of plasma cells, the N… …   Dictionary of molecular biology

  • amyloid A — AA amyloid a pathological fibrillar low molecular weight protein formed by cleavage of serum amyloid A (SAA) protein. It is deposited in the tissues secondary to chronic inflammatory conditions; see AA amyloidosis, under amyloidosis …   Medical dictionary

  • Protein C — Not to be confused with C peptide, C reactive protein, or protein kinase C. Protein C (inactivator of coagulation factors Va and VIIIa) Tertiary structure of human activated protein C (minus the Gla domain …   Wikipedia

  • acute phase protein — Proteins found in the serum of organisms showing acute inflammation. In particular C reactive protein and serum amyloid A protein …   Dictionary of molecular biology

  • acute phase protein — any of the non antibody proteins, produced mainly in the liver, found in increased amounts in serum during the acute phase response; they include C reactive protein, serum amyloid A protein, fibrinogen, α1 acid glycoprotein, and… …   Medical dictionary

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