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Choriocarcinoma

Translation
Choriocarcinoma
A highly malignant tumor that arises from trophoblastic cells within the uterus. Choriocarcinoma tends to be invasive and to metastasize early and widely through both the venous and lymphatic systems. Choriocarcinoma is one of the two types of gestational trophoblastic tumor, the other being hydatidiform mole. Choriocarcinoma may follow any type of pregnancy. It is especially likely to occur with a hydatidiform mole (molar pregnancy). About 2 to 3% of hydatidiform moles are complicated by the development of choriocarcinoma. The prognosis for women with metastatic choriocarcinoma was once grim. It has markedly improved with the advent of multidrug chemotherapy. Patients with high-risk metastatic disease usually need aggressive multidrug chemotherapy. Women with low-risk metastatic disease are sometimes treated with a single drug. Overall, the cure rate for high-risk patients is 60 to 80%.
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A highly malignant neoplasm derived from placental syncytial trophoblasts and cytotrophoblasts which forms irregular sheets and cords, which are surrounded by irregular “lakes” of blood; villi are not formed; neoplastic cells invade blood vessel s. Hemorrhagic metastases develop relatively early in the course of the illness, and are frequently found in the lungs, liver, brain, and vagina, and various other pelvic organs; c. may follow any type of pregnancy, especially hydatidiform mole, and occasionally originates in teratoid neoplasms of the ovaries or testes. SYN: chorioepithelioma.

Medical dictionary. 2011.

  
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  • Choriocarcinoma — Classification and external resources ICD 10 C58 ICD 9 181 …   Wikipedia

  • choriocarcinoma — noun Etymology: New Latin, from chorion + carcinoma Date: 1901 a malignant tumor typically developing in the uterus from the trophoblast …   New Collegiate Dictionary

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  • choriocarcinoma — /kawr ee oh kahr seuh noh meuh, kohr /, n., pl. choriocarcinomas, choriocarcinomata / meuh teuh/. Pathol. chorioma. [1900 05; CHORIO + CARCINOMA] * * * …   Universalium

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  • Gestational choriocarcinoma — is a malignant trophoblastic tumour arising from any gestational event during pregnancy in the reproductive female.Women with gestational choriocarcinoma may present with abnormal vaginal bleeding, persistent markedly elevated beta;hCG, or a… …   Wikipedia