renin substrate

renin substrate
angiotensinogen.

Medical dictionary. 2011.

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  • renin — A term originally used for a pressor substance obtained from rabbits kidneys, now an enzyme that converts angiotensinogen to angiotensin I. SYN: angiotensinogenase. * * * re·nin rē nənalso ren ən n a proteolytic enzyme of the blood that is… …   Medical dictionary

  • renin — n. an enzyme released into the blood by the kidney in response to stress. It reacts with a substrate from the liver to produce angiotensin, which causes constriction of blood vessels and thus an increase in blood pressure. Excessive production of …   The new mediacal dictionary

  • Discovery and development of renin inhibitors — Renin inhibitors are antihypertensive drugs that inhibit the first and rate limiting step of the renin angiotensin aldosterone system (RAAS). Since the 1970s scientists have been trying to develop potent inhibitors with acceptable oral… …   Wikipedia

  • Angiotensin — causes blood vessels to constrict, and drives blood pressure up. It is part of the renin angiotensin system, which is a major target for drugs that lower blood pressure. Angiotensin also creates aldosterone, which causes the tubules of the… …   Wikipedia

  • angiotensinogen — The substrate for renin whereupon through enzymatic action angiotensin I is liberated; an abundant α2 globulin that circulates in the blood plasma. SYN: angiotensin precursor. * * * an·gio·ten·sin·o·gen ten(t) sin ə jən n …   Medical dictionary

  • angiotensin — A peptide hormone. Angiotensinogen (renin substrate) is a 60 kD polypeptide released from the liver and cleaved in the circulation by renin to form the biologically inactive decapeptide angiotensin I. This is in turn cleaved to form active… …   Dictionary of molecular biology

  • Arda Green — Arda Alden Green (* 7. Mai 1899 in Prospect, Pennsylvania, USA; † 23. Januar 1958 in New York) war eine US amerikanische Biochemikerin. Zu den größten wissenschaftlichen Leistungen der Spezialistin für Proteinkristallisierung gehörte die… …   Deutsch Wikipedia

  • PRS — Personality Rating Scale; Pierre Robin syndrome; plasma renin substrate; Prieto syndrome; proctorectosigmoidoscopy …   Medical dictionary

  • PRS — • Personality Rating Scale; • Pierre Robin syndrome; • plasma renin substrate; • Prieto syndrome; • proctorectosigmoidoscopy …   Dictionary of medical acronyms & abbreviations

  • system — 1. [TA] A consistent and complex whole made up of correlated and semiindependent parts. A complex of functionally related anatomic structures. 2. The entire organism seen as a complex organization of parts. 3. Any complex of structures… …   Medical dictionary

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