nitroblue tetrazolium test

nitroblue tetrazolium test
(for neutrophil microbicidal function) neutrophils are incubated with latex particles and nitroblue tetrazolium (NBT). Normally phagocytosis of the particles is accompanied by reduction of NBT to a blue formazan pigment; absence of NBT reduction indicates a defect in some of the metabolic pathways involved in intracellular microbial killing, as seen in chronic granulomatous disease. Called also NBT t.

Medical dictionary. 2011.

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  • nitroblue tetrazolium — ni·tro·blue tet·ra·zo·li·um (niґtro bloo tet″rə zoґle əm) a yellow water soluble dye that on reduction is converted to a dark blue water insoluble formazan; see also under test …   Medical dictionary

  • Cloruro de nitroblue tetrazolium — Nombre (IUPAC) …   Wikipedia Español

  • test — 1. To prove; to try a substance; to determine the chemical nature of a substance by means of reagents. 2. A method of examination, as to determine the presence or absence of a definite disease or of some substance in any of the fluids, tissues,… …   Medical dictionary

  • tetrazolium — Any of a group of organic salts having the general structure that on reduction (cleaving the 2,3 bond) yields a colored insoluble formazan; used as a reagent in oxidative enzyme histochemistry. nitroblue t. ( …   Medical dictionary

  • NBT test — nitroblue tetrazolium t …   Medical dictionary

  • fructosamine test — determination of the serum fructosamine level by measurement of the reduction of nitroblue tetrazolium to purple under alkaline conditions; it is used as an index of the average glycemic state over the preceding two to three weeks and is used to… …   Medical dictionary

  • formazan — A water insoluble colored compound of the general structure, RNH N=CR′ N=NR″, formed by reduction of a tetrazolium salt in the histochemical demonstration of oxidative enzymes; the R s are usually phenyl groups; examples include neotetrazolium,… …   Medical dictionary

  • NBT — Abbreviation for nitroblue tetrazolium. * * * Nature Based Therapy; nitroblue tetrazolium; non tumor bearing; normal breast tissue * * * nitroblue tetrazolium; see under test …   Medical dictionary

  • Chronic granulomatous disease — Classification and external resources Superoxide ICD 10 D …   Wikipedia

  • List of medical abbreviations: N — v · d · …   Wikipedia

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