Paul-Bunnell-Davidsohn test

Paul-Bunnell-Davidsohn test
a type of heterophile antibody test for infectious mononucleosis, a modification of the Paul-Bunnell test that differentiates among three types of heterophile sheep erythrocyte agglutinins: those associated with infectious mononucleosis, those associated with serum sickness, and natural antibodies against Forssman antigen. The patient's serum is absorbed with guinea pig kidney cells or with beef erythrocytes and centrifuged. Unabsorbed serum has an abnormally high heterophile antibody titer in infectious mononucleosis and serum sickness. Absorption with guinea pig kidney removes Forssman antibodies and serum sickness heterophile antibodies. Absorption with beef erythrocytes removes heterophile antibodies associated with infectious mononucleosis and serum sickness. Called also Davidsohn differential absorption t.

Medical dictionary. 2011.

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  • Paul-Bunnell-Davidsohn test — Paul Bun·nell Da·vid·sohn test (pawlґ bə nelґ daґvid son) [J.R. Paul; W.W. Bunnell; Israel Davidsohn, American pathologist, 1895–1979] see under test …   Medical dictionary

  • Paul-Bunnell-Test — Die Paul Bunnell Reaktion ist ein klassisches diagnostisches Testverfahren in der Medizin, mit dem heterophile Antikörper gegen rote Blutkörperchen von Hammeln (Hammelerythrozyten) nachgewiesen werden. Der Test dient zum Nachweis einer akuten… …   Deutsch Wikipedia

  • Paul-Bunnell-Reaktion — Die Paul Bunnell Reaktion ist ein klassisches diagnostisches Testverfahren in der Medizin, mit dem heterophile Antikörper gegen rote Blutkörperchen von Hammeln (Hammelerythrozyten) nachgewiesen werden. Der Test dient zum Nachweis einer akuten… …   Deutsch Wikipedia

  • Davidsohn differential absorption test — Da·vid·sohn differential absorption test (daґvid sən) [Israel Davidsohn, American pathologist, 1895–1979] Paul Bunnell Davidsohn test …   Medical dictionary

  • Davidsohn differential absorption test — Paul Bunnell Davidsohn t …   Medical dictionary

  • mononucleosis spot test — monospot test a type of heterophile antibody test for infectious mononucleosis, a modification of the Paul Bunnell Davidsohn test, using horse erythrocytes instead of sheep erythrocytes; no centrifugation step is needed and the whole test is… …   Medical dictionary

  • heterophil antibody test — heterophile antibody test any of several tests for heterophile antibodies associated with infectious mononucleosis; the most common ones are the monospot test and the Paul Bunnell Davidsohn test …   Medical dictionary

  • differential test for infectious mononucleosis — Paul Bunnell Davidsohn t …   Medical dictionary

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