sperm immobilization test

sperm immobilization test
(for male factor infertility) a test for antisperm antibodies as a cause of infertility, based on the fact that spermatozoa with such surface antibodies lose their ability to move if complement is present (as it normally is in the female reproductive tract). Serum from the patient is incubated with motile sperm and complement is added. After one hour the mixture is checked to calculate the percentage of formerly motile sperm that can no longer move; a 50 per cent reduction in motility is a positive result for presence of antisperm antibodies. Called also Isojima t.

Medical dictionary. 2011.

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