utrophin

utrophin
u·tro·phin (uґtrə-fin) a homologue of dystrophin with similar structure and function; it contains an actin-binding N-terminus and a C-terminus that interacts with dystroglycan protein components, links the actin cytoskeleton to the extracellular matrix, and is ubiquitously expressed. In muscle tissue, it is located at the neuromuscular synapse and myotendinous junctions, and participates in postsynaptic membrane maintenance and acetylcholine receptor clustering.

Medical dictionary. 2011.

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  • Utrophin — Utrophin, also known as UTRN, is a human gene.cite web | title = Entrez Gene: UTRN utrophin| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=7402| accessdate = ] The protein encoded by this gene is a… …   Wikipedia

  • utrophin — (= dystrophin associated protein) Autosomal homologue of dystrophin (395kD) localized near the neuromuscular junction in adult muscle, though in the absence of dystrophin (ie. in Duchenne muscular dystrophy) utrophin is also located on the… …   Dictionary of molecular biology

  • utrophin — noun A cytoskeleton protein homologous with dystrophin …   Wiktionary

  • PGM5 — Phosphoglucomutase 5, also known as PGM5, is a human gene.cite web | title = Entrez Gene: PGM5 phosphoglucomutase 5| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=5239| accessdate = ] PBB Summary section… …   Wikipedia

  • Duchenne muscular dystrophy — Classification and external resources Histopathology of gastrocnemius muscle from patient who died of pseudohypertrophic muscular dystrophy, Duchenne type. Cross section of muscle shows extensive replacement of muscle fibers by adipose cells …   Wikipedia

  • Dystroglycan — 1 (dystrophin associated glycoprotein 1) PDB rendering based on 1u2c …   Wikipedia

  • Actin-binding protein — Actin binding proteins (also known as ABP) are proteins that bind to actin. This may mean ability to bind actin monomers, or polymers, or both.Many actin binding proteins, including α actinin, β spectrin, dystrophin, utrophin and fimbrin, do this …   Wikipedia

  • SNTA1 — Syntrophin, alpha 1 (dystrophin associated protein A1, 59kDa, acidic component), also known as SNTA1, is a human gene.cite web | title = Entrez Gene: SNTA1 syntrophin, alpha 1 (dystrophin associated protein A1, 59kDa, acidic component)| url =… …   Wikipedia

  • SNTB2 — Syntrophin, beta 2 (dystrophin associated protein A1, 59kDa, basic component 2), also known as SNTB2, is a human gene.cite web | title = Entrez Gene: SNTB2 syntrophin, beta 2 (dystrophin associated protein A1, 59kDa, basic component 2)| url =… …   Wikipedia

  • Microtubule — Space filling model of a microtubule segment derived from cryo electron microscopy. The protofilaments are seen running along the axis of the segment. The microtubule (+) end is towards the top of the image.[1] Microtubules are a component of the …   Wikipedia

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