Creatine
A compound the body synthesizes (makes) and then utilizes to store energy. The storage of energy occurs when phosphate molecules are attached to creatine to create creatine phosphate. Creatine phosphate is capable of donating phosphate to ADP in order to make ATP. ATP can then be converted into ADP with release of energy. Creatine is sold as a dietary supplement and is used by athletes as a "legal steroid" to increase muscle bulk. There has been some concern about the long-term safety of creatine, particularly as to whether it may cause digestive, muscular and cardiovascular problems and possibly raise the risk of cancer.
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N-(Aminoiminomethyl)-N-methylglycine; occurs in urine, sometimes as such, but generally as creatinine, and in muscle, generally as phosphocreatine. Elevated in urine in individuals with muscular dystrophy.
- c. kinase (CK) an enzyme catalyzing the reversible transfer of phosphate from phosphocreatine to ADP, forming c. and ATP; of importance in muscle contraction. Certain isozymes are elevated in plasma following myocardial infarctions. SYN: c. phosphokinase.
- c. phosphokinase (CPK) SYN: c. kinase.

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cre·atine 'krē-ə-.tēn, -ət-ən n a white crystalline nitrogenous substance C4H9N3O2 found esp. in vertebrate muscle either free or as phosphocreatine

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n.
a product of protein metabolism found in muscle. Its phosphate, creatine phosphate (phosphocreatine, phosphagen), acts as a store of high-energy phosphate in muscle and serves to maintain adequate amounts of ATP (the source of energy for muscular contraction).

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cre·a·tine (kreґə-tin) [Gr. kreas flesh] an amino acid formed by methylation of guanidinoacetic acid, found in vertebrate tissues, particularly in muscle. Phosphorylated creatine (see phosphocreatine) is an important storage form of high energy phosphate, the energy source for muscle contraction.

Medical dictionary. 2011.

Look at other dictionaries:

  • Creatine — Créatine Créatine Général Nom IUPAC 2 (carbamimidoyl methyl amino)acetic acid No CAS …   Wikipédia en Français

  • Créatine —         …   Wikipédia en Français

  • créatine — [ kreatin ] n. f. • 1823; du gr. kreas, kreatos « chair » ♦ Biochim. Composé azoté, de formule C4H9N3O2, qui joue un rôle essentiel dans la contraction musculaire. ● créatine nom féminin (grec kreas, atos, chair) Substance azotée de l organisme,… …   Encyclopédie Universelle

  • creatine — 1834, from Fr. creatine, from Gk. kreas flesh, meat (see RAW (Cf. raw)) + chemical suffix INE (Cf. ine) (2). Organic base discovered by French physicist Michel Eugène Chevreul (1786 1889) in the juice of flesh and named by him …   Etymology dictionary

  • creatine — creatine. См. креатин. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • creatine — [krē′ə tēn΄, krē′ətin] n. [< Gr kreas, flesh (see CRUDE) + INE3] a crystalline substance, C4H9N3O2, present in muscle tissue, usually in the form of phosphocreatine …   English World dictionary

  • Creatine — For the use of creatine to increase athletic performance, see Creatine supplements. Not to be confused with creatinine. Creatine …   Wikipedia

  • creatine — noun Etymology: French créatine, from Greek kreat , kreas flesh more at raw Date: 1840 a white crystalline nitrogenous substance C4H9N3O2 found especially in the muscles of vertebrates either free or as phosphocreatine; also a synthetic …   New Collegiate Dictionary

  • creatine — n. a product of protein metabolism found in muscle. Its phosphate, creatine phosphate (phosphocreatine, phosphagen), acts as a store of high energy phosphate in muscle and serves to maintain adequate amounts of ATP (the source of energy for… …   The new mediacal dictionary

  • creatine — /ˈkriətən/ (say kreeuhtuhn) noun an amino acid, NH2C(=NH)NH+(CH3)CH2COO , found mainly in combined form as creatine phosphate, present in the tissues of all vertebrates and some invertebrates, and used to synthesise adenosine triphosphate under… …   Australian English dictionary

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