erythropoietin

erythropoietin
A sialic acid-containing protein that enhances erythropoiesis by stimulating formation of proerythroblasts and release of reticulocytes from bone marrow; it is formed by the kidney and liver, and possibly by other tissues, and can be detected in human plasma and urine. SYN: erythropoietic hormone (2), hematopoietin, hemopoietin.

* * *

eryth·ro·poi·e·tin -'pȯi-ət-ən n a hormonal substance that is formed esp. in the kidney and stimulates red blood cell formation abbr. EPO see EPOGEN

* * *

n.
a hormone secreted by certain cells in the kidney in response to a reduction in the amount of oxygen reaching the tissues. Erythropoietin increases the rate of red cell production (erythropoiesis) and is the mechanism by which the rate of erythropoiesis is controlled.

* * *

eryth·ro·poi·e·tin (ə-rith″ro-poiґə-tin) a glycoprotein hormone secreted chiefly by the kidney in the adult and by the liver in the fetus, which acts on the bone marrow cells to stimulate erythropoiesis. Called also hematopoietin and hemopoietin.

Medical dictionary. 2011.

Игры ⚽ Поможем решить контрольную работу

Look at other dictionaries:

  • Erythropoietin — Available structures …   Wikipedia

  • erythropoietin — [e rith΄rōpoi′ə tin] n. a hormone that stimulates erythropoiesis, produced mainly in the kidneys of higher organisms …   English World dictionary

  • Erythropoietin — Erythropoetin Oberflächenmodell von Erythropoetin (Mitte) im Komplex mit seinem Rezeptor, nach PDB  …   Deutsch Wikipedia

  • erythropoietin — n. a hormone secreted by certain cells in the kidney in response to a reduction in the amount of oxygen reaching the tissues. Erythropoietin increases the rate of red cell production (erythropoiesis) and is the mechanism by which the rate of… …   The new mediacal dictionary

  • erythropoietin — A substance that is naturally produced by the kidneys, and that stimulates the bone marrow to make red blood cells. When erythropoietin is made in the laboratory, it is called epoetin alfa or epoetin beta …   English dictionary of cancer terms

  • Erythropoietin receptor — The erythropoietin receptor is a 66 kDa peptide and is a member of the cytokine receptor family. The receptor is tyrosine phosphorylated upon binding by erythropoietin and associates with and activates the tyrosine kinase, JAK2, which activates… …   Wikipedia

  • Erythropoietin (EPO) — A hormone produced by the kidney that promotes the formation of red blood cells in the bone marrow. EPO is a glycoprotein (a protein with a sugar attached to it). Human EPO has a molecular weight of 34,000. The kidney cells that make EPO are… …   Medical dictionary

  • Erythropoietin test — A test of the hormone erythropoietin (EPO) in blood. An abnormal level of EPO may mean bone marrow or kidney disease or EPO abuse. Testing EPO blood levels is thus of value if: {{}}Too little EPO might be responsible for too few red blood cells… …   Medical dictionary

  • erythropoietin — noun Date: 1948 a glycoprotein hormone formed especially in the kidney and stimulating red blood cell formation …   New Collegiate Dictionary

  • erythropoietin — Glycoprotein (46 kD) produced in the kidney and that regulates the production of red blood cells in the marrow. Higher concentrations are required to stimulate BFU Es than CFU Es to produce erythrocytes. Recombinant EPO is now being used… …   Dictionary of molecular biology

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”