Disease, Castleman
A disorder of lymphoid tissue (lymphadenopathy) with massive overgrowth (hyperplasia) of lymph nodes ("swollen glands"), most commonly affecting the nodes between the lungs (in the mediastinum). There are two quite different forms of Castleman disease. One form, found in 90% cases, is a localized kind of lympadenopathy. It usually causes no symptoms, follows an indolent (lazy) course and can be cured simply by excision (surgical removal). The far more ominous form of Castleman disease, encountered in 10% of cases, is a multicentric lymphadenopathy with progressive systemic signs and symptoms such as fever and anemia. This rapidly progressive multicentric type of Castleman disease is associated with infection by human herpesvirus 8 (HHV-8). The disease was first described by B. Castleman and colleagues in 1956.

Medical dictionary. 2011.

Look at other dictionaries:

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  • Castleman-Krankheit — Morbus Castleman (Castleman Krankheit) ist definiert als Hypertrophie der Lymphknoten mit angiofollikulärer Lymph Hyperplasie.[1] Das heißt, einerseits sind einer oder mehrere Lymphknoten dadurch vergrößert, dass jede einzelne Zelle ein größeres… …   Deutsch Wikipedia

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  • Morbus Castleman — Mikrofoto von Morbus Castleman, Hyaliner vaskulärer Typ, mit der charakteristische zwiebelschalenartiger Form. HE Färbung. Morbus Castleman (Castleman Krankheit) ist definiert als Hypertrophie der Lymphknoten mit angiofollikulärer Lymph… …   Deutsch Wikipedia

  • Lymphatic disease — Classification and external resources MeSH D008206 Lymphatic disease is a class of disorders which directly affect the components of the lymphatic system. Examples include Castleman s disease …   Wikipedia

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