Disease, Kimmelstiel-Wilson

Disease, Kimmelstiel-Wilson
Diabetic nephropathy (kidney disease). Kimmelstiel-Wilson disease is a kidney condition associated with long-standing diabetes. It affects the network of tiny blood vessels (the microvasculature) in the glomerulus, a key structure in the kidney that is composed of capillary blood vessels and which is critically necessary for the filtration of the blood. Features of Kimmelstiel-Wilson disease include the nephrotic syndrome with excessive filtration of protein into the urine (proteinuria), high blood pressure (hypertension), and progressively impaired kidney function. When severe, Kimmelstiel-Wilson disease leads to kidney failure, end-stage renal disease, and the need for chronic kidney dialysis or a kidney transplant. The disorder is named for Paul Kimmelstein (1900-70), a German- born pathologist in the U.S., and Clifford Wilson (1906-), an English physician. It is also known as intercapillary glomerulonephritis.

Medical dictionary. 2011.

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  • Wilson — Clifford, English physician, *1906. See Kimmelstiel W. disease, Kimmelstiel W. syndrome. James, English anatomist, physiologist, and surgeon, 1765–1821. See W. muscle. Miriam G., U.S. pediatrician, *1922. See W. Mikity syndrome. Samuel A. Kinnier …   Medical dictionary

  • Kimmelstiel — Paul, German pathologist in the U.S., 1900–1970. See K. Wilson disease, K. Wilson syndrome …   Medical dictionary

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  • Diabetic nephropathy — Classification and external resources Photomicrography of nodular glomerulosclerosis in Kimmelstein Wilson syndrome. Source: CDC ICD 10 E10.2, E11.2, E12.2, E13.2, E …   Wikipedia

  • Diabetische Nephropathie — Klassifikation nach ICD 10 N08.3* Glomeruläre Krankheiten bei Diabetes mellitus …   Deutsch Wikipedia

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