gentamicin

gentamicin
A broad spectrum antibiotic of the aminoglycoside class, obtained from Micromonospora purpurea and M. echinospora, that inhibits the growth of both Gram-positive and Gram-negative bacteria; the sulfate salt is used medicinally.

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gen·ta·mi·cin .jent-ə-'mīs-ən n a broad-spectrum aminoglycoside antibiotic mixture that is derived from two actinomycetes of the genus Micromonospora (M. purpurea and M. echinospora) and is extensively used in the form of the sulfate in treating infections esp. of the urinary tract

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n.
an aminoglycosides antibiotic used to treat infections caused by a wide range of bacteria. It can be administered by injection or applied in a cream to the skin or in drops to the ears and eyes. Kidney and ear damage may occur at high doses. Trade names: Cidomycin, Garamycin, Genticin.

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gen·ta·mi·cin (jen″tə-miґsin) an aminoglycoside antibiotic complex derived from Micromonospora echinospora, consisting of components designated A, B, C, etc. The form in clinical use is a mixture of three fractions of the C component (C1, C1A, C2); it is effective against a wide range of aerobic gram-negative bacilli, especially the Enterobacteriaceae and Pseudomonas, and some gram-positive bacteria.

Medical dictionary. 2011.

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  • Gentamicin — Systematic (IUPAC) name (3R,4R,5R) 2 {[(1S,2S …   Wikipedia

  • Gentamicin —   [Kurzwort] das, s, Gentamizin, aus Kulturfiltraten verschiedener Micromonospora Arten gewonnenes Breitbandantibiotikum aus der Gruppe der Aminoglykosidantibiotika; besteht im Wesentlichen aus drei Komponenten, die (ähnlich wie Streptomycin) aus …   Universal-Lexikon

  • gentamicin — gentamìcīn m <G gentamicína> DEFINICIJA farm. antibiotik širokog spektra, dobiva se iz aktinomicetne bakterije Micromonospora purpurea; primjenjuje se parenteralno u slučajevima gama negativnih infekcija ETIMOLOGIJA engl. gentian violet:… …   Hrvatski jezični portal

  • gentamicin — [jent΄ə mī′sin] n. [< gentian violet (color of the organism) + MYCIN] a broad spectrum antibiotic obtained from soil actinomycetes (genus Micromonospora), used in treating a wide variety of serious infections …   English World dictionary

  • Gentamicin — Wikipedia:Redaktion Chemie/ausgeblendete Strukturformel Allgemeines Freiname Gentamicin Andere Namen Gentamycin Summenformel Stoffgemisch …   Deutsch Wikipedia

  • Gentamicin 2'-N-acetyltransferase — In enzymology, a gentamicin 2 N acetyltransferase (EC number|2.3.1.59) is an enzyme that catalyzes the chemical reaction:acetyl CoA + gentamicin C1a ightleftharpoons CoA + N2 acetylgentamicin C1aThus, the two substrates of this enzyme are acetyl… …   Wikipedia

  • Gentamicin 3'-N-acetyltransferase — In enzymology, a gentamicin 3 N acetyltransferase (EC number|2.3.1.60) is an enzyme that catalyzes the chemical reaction:acetyl CoA + gentamicin C ightleftharpoons CoA + N3 acetylgentamicin CThus, the two substrates of this enzyme are acetyl CoA… …   Wikipedia

  • Gentamicin 2"-nucleotidyltransferase — In enzymology, a gentamicin 2 nucleotidyltransferase (EC number|2.7.7.46) is an enzyme that catalyzes the chemical reaction:nucleoside triphosphate + gentamicin ightleftharpoons diphosphate + 2 nucleotidylgentamicinThus, the two substrates of… …   Wikipedia

  • gentamicin sulfate — [USP] the sulfate salt of gentamicin, applied topically to the skin, ear canal, or conjunctiva or administered intramuscularly or intravenously in the treatment of a wide variety of infections caused by susceptible gram negative organisms …   Medical dictionary

  • gentamicin — noun Etymology: alteration of earlier gentamycin, from gentian violet + kanamycin; from the color of the actinomycete Date: 1963 a broad spectrum antibiotic mixture derived from an actinomycete (Micromonospora purpurea or M. echinospora) and… …   New Collegiate Dictionary

  • gentamicin — A group of aminoglycoside antibiotics produced by Micromonospora spp. Members include the closely related gentamycins C1, C2 and C1a, together with gentamycin A. They inhibit protein synthesis on 70S ribosomes by binding to the 23S core protein… …   Dictionary of molecular biology

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