goserelin

goserelin
A synthetic decapeptide agonist analog of the LHRH (GnRH). It inhibits pituitary gonadotropin secretion and is used in the treatment of prostate cancer, breast cancer, endometriosis, and for prethinning the endometrium before endometrial ablation or resection.

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n.

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go·se·rel·in (goґsə-rel″in) a synthetic gonadotropin-releasing hormone analogue; upon administration it initially stimulates release of follicle-stimulating hormone and luteinizing hormone and on prolonged administration later suppresses them.

Medical dictionary. 2011.

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  • Goserelin — drugbox IUPAC name = N [1 [1 [1 [1 [1 [1 [1 [2 [(carbamoylamino)carbamoyl] pyrrolidin 1 yl] 5 (diaminomethylideneamino) 1 oxo pentan 2 yl] carbamoyl] 3 methyl butyl] carbamoyl] 2 tert butoxy ethyl] carbamoyl] 2 (4 hydroxyphenyl) ethyl] carbamoyl] …   Wikipedia

  • goserelin — A drug that belongs to the family of drugs called gonadotropin releasing hormone analogs. Goserelin is used to block hormone production in the ovaries or testicles …   English dictionary of cancer terms

  • goserelin acetate — the acetate salt of goserelin, used to treat breast and prostate carcinomas and endometriosis, and to thin the endometrium prior to endometrial ablation; administered by subcutaneous implant …   Medical dictionary

  • goserelin — go·se·rel·in (gō sə rĕlʹĭn) n. A synthetic peptide analogue of gonadotropin releasing hormone used to treat prostate cancer, endometriosis, and advanced breast cancer.   [Blend of gonadorelin(from gonadotropin releasing hormone + in), and… …   Universalium

  • goserelin — n. a gonadorelin analogue that is used in the treatment of endometriosis, prostate cancer, and fibroids, being administered by subcutaneous depot injection at one or three monthly intervals. It is also used in the treatment of infertility by in… …   The new mediacal dictionary

  • Гозерелин (Goserelin) — см. Аналог лютеинизирующего гормона. Источник: Медицинский словарь …   Медицинские термины

  • ГОЗЕРЕЛИН — (goserelin) см. Аналог лютеинизирующего гормона …   Толковый словарь по медицине

  • Prostate cancer — is a disease in which cancer develops in the prostate, a gland in the male reproductive system. It occurs when cells of the prostate mutate and begin to multiply out of control. These cells may spread (metastasize) from the prostate to other… …   Wikipedia

  • Management of prostate cancer — Treatment for prostate cancer may involve active surveillance, surgery, radiation therapy including brachytherapy (prostate brachytherapy) and external beam radiation therapy, High intensity focused ultrasound (HIFU), chemotherapy, cryosurgery,… …   Wikipedia

  • Subcutaneous injection — A subcutaneous injection is administered as a bolus into the subcutis, [DorlandsDict|four/000053802|subcutaneous injection] the layer of skin directly below the dermis and epidermis, collectively referred to as the cutis. Subcutaneous injections… …   Wikipedia

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