heparan sulfate

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hep·a·ran sulfate 'hep-ə-.ran- n a sulfated glycosaminoglycan that accumulates in bodily tissues in abnormal amounts in some mucopolysaccharidoses called also heparitin sulfate

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hep·a·ran sul·fate (hepґə-ran) a glycosaminoglycan occurring in the cell membrane of most cells. It consists of repeating disaccharide units in specific linkage, each composed of a glucosamine residue linked to a uronic acid, either glucuronic acid or L-iduronic acid, which may be sulfated. The glucosamine residues frequently contain acetyl or sulfate group substituents. It is an accumulation product in several mucopolysaccharidoses.

Medical dictionary. 2011.

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  • Heparan sulfate — (HS) is a linear polysaccharide found in all animal tissues. It occurs as a proteoglycan (PG) in which two or three HS chains are attached in close proximity to cell surface or extracellular matrix proteins. [cite book | title=Proteoglycans:… …   Wikipedia

  • heparan sulfate — noun A polysaccharide found, associated with protein, in all animal tissue; it has a regulatory function in several biological activities …   Wiktionary

  • Heparan sulfate analogue — Heparan sulfate analogues are polymers engineered to mimic several properties of heparan sulfates. [1] They can be constituted with a backbone of polysaccharides, such as poly glucose or glucuronates [2] or a polyester such as co polymers of… …   Wikipedia

  • (heparan sulfate)-glucosamine N-sulfotransferase — In enzymology, a [heparan sulfate] glucosamine N sulfotransferase (EC number|2.8.2.8) is an enzyme that catalyzes the chemical reaction:3 phosphoadenylyl sulfate + [heparan sulfate] glucosamine ightleftharpoons adenosine 3 ,5 bisphosphate +… …   Wikipedia

  • (heparan sulfate)-glucosamine 3-sulfotransferase 1 — In enzymology, a [heparan sulfate] glucosamine 3 sulfotransferase 1 (EC number|2.8.2.23) is an enzyme that catalyzes the chemical reaction:3 phosphoadenylyl sulfate + [heparan sulfate] glucosamine ightleftharpoons adenosine 3 ,5 bisphosphate +… …   Wikipedia

  • (heparan sulfate)-glucosamine 3-sulfotransferase 2 — In enzymology, a [heparan sulfate] glucosamine 3 sulfotransferase 2 (EC number|2.8.2.29) is an enzyme that catalyzes the chemical reaction:3 phosphoadenylyl sulfate + [heparan sulfate] glucosamine ightleftharpoons adenosine 3 ,5 bisphosphate +… …   Wikipedia

  • (heparan sulfate)-glucosamine 3-sulfotransferase 3 — In enzymology, a [heparan sulfate] glucosamine 3 sulfotransferase 3 (EC number|2.8.2.30) is an enzyme that catalyzes the chemical reaction:3 phosphoadenylyl sulfate + [heparan sulfate] glucosamine ightleftharpoons adenosine 3 ,5 bisphosphate +… …   Wikipedia

  • heparan sulfate sulfamidase — hep·a·ran sul·fate sul·fam·i·dase (hepґə ran sulґfāt səl famґĭ dās) heparan N sulfatase …   Medical dictionary

  • Heparan-alpha-glucosaminide N-acetyltransferase — In enzymology, a heparan alpha glucosaminide N acetyltransferase (EC number|2.3.1.78) is an enzyme that catalyzes the chemical reaction:acetyl CoA + heparan sulfate alpha D glucosaminide ightleftharpoons CoA + heparan sulfate N acetyl alpha D… …   Wikipedia

  • heparan N-sulfatase — An enzyme that participates in the stepwise degradation of heparan sulfate; heparan N sulfatase hydrolyzes the sulfate moiety attached to the amino group of the glucosamine residue of heparan sulfate; a deficiency of this enzyme is associated… …   Medical dictionary

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