Effect, founder
A population group with an unusual frequency of a gene due to there having been only a small number of original members ("founders") one or more of whom had that gene. For example, the gene for Huntington disease was introduced into the Lake Maracaibo region of Venezuela early in the 19th century, so there are now over a hundred persons with Huntington disease and at least 900 persons at risk for that deadly disease in that region, the largest known aggregation known in the world with the Huntington gene.

Medical dictionary. 2011.

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  • Founder — may refer to: * Founder (noun) With respect to a settlement, organization, company or enterprise, the person who started or founded (as if forging steel) it. * Founder (noun) A metalworker operating a foundry. * Foundering (verb) – Sinking, used… …   Wikipedia

  • founder effect — founder effect. См. эффект основателя. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Founder effect — In population genetics, the founder effect refers to the loss of genetic variation when a new colony is established by a very small number of individuals from a larger population. It was first fully outlined by Ernst Mayr in 1952 [Provine, W.B.… …   Wikipedia

  • Founder-Effect — Beispiel: eine Stammpopulation (links) und drei mögliche Gründerpopulationen (rechts) Der Gründereffekt (Founder Effect) beschreibt eine genetische Abweichung einer isolierten Population oder Gründerpopulation (z. B. auf einer Insel) von der… …   Deutsch Wikipedia

  • Founder-Effekt — Beispiel: eine Stammpopulation (links) und drei mögliche Gründerpopulationen (rechts) Der Gründereffekt (Founder Effect) beschreibt eine genetische Abweichung einer isolierten Population oder Gründerpopulation (z. B. auf einer Insel) von der… …   Deutsch Wikipedia

  • founder principle — См. founder effect …   Dictionary of invertebrate zoology

  • founder effect — noun Date: 1970 the effect on the resulting gene pool that occurs when a new isolated population is founded by a small number of individuals possessing limited genetic variation relative to the larger population from which they have migrated …   New Collegiate Dictionary

  • Effect of Hurricane Katrina on Tulane University — As a result of Hurricane Katrina and its effects on New Orleans, Tulane University was closed for the second time in its history mdash;the first being during the American Civil War. The university closed for four months during Katrina, as… …   Wikipedia

  • Founder effect — The positive effect on gene frequency when a population (a colony) has only a small number of original settlers (founders) one or more of whom had that gene. For example, the gene for Huntington disease was introduced into the Lake Maracaibo… …   Medical dictionary

  • effect — The result or consequence of an action. [L. efficio, pp. effectus, to accomplish, fr. facio, to do] abscopal e. a reaction produced following irradiation but occurring outside the zone of actual radiation absorption. additive e. an e. wherein two …   Medical dictionary

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