hyposplenism

hyposplenism
Absent or reduced splenic function, usually due to surgical removal, congenital aplasia, tumor replacement, or splenic vascular accident. Red cell abnormalities, including the presence of inclusions, nucleated erythrocytes, and target cells, are commonly present. Patients with h. are at increased risk of bacterial sepsis, especially due to pneumococcus.

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hy·po·splen·ism (hi″po-splenґiz-əm) diminished functioning of the spleen.

Medical dictionary. 2011.

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