interleukin-10

interleukin-10
A cytokine derived from helper T-cell lymphocytes (TH2) that inhibits γ-interferon (IFNγ) and IL-2 secretion by T cell lymphocytes (TH1) and inhibits mononuclear cell inflammation.

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(IL-10) a cytokine produced by activated macrophages, certain lymphocytes, and other cells that decreases both innate and T cell–mediated immune inflammation; it inhibits the production of cytokines by activated T cells, plays a role in B cell activation, inhibits production of interferon-γ, and blocks antigen presentation and macrophage formation of IL-1, IL-6, and tumor necrosis factor.

Medical dictionary. 2011.

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