Gene silencing
A mechanism by which cells shut down large sections of chromosomal DNA. Gene silencing is done by incorporating the DNA to be silenced into a form of DNA called heterochromatin that is already silent. The process of gene silencing is important for the differentiation of many different types of cells.

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negative regulation of gene expression; it includes processes that inhibit transcription of genes, such as DNA methylation, and posttranscriptional processes, such as the degradation of messenger RNA by RNA interference.

Medical dictionary. 2011.

Look at other dictionaries:

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