Amplification
Making multiple copies of a gene or of any sequence of DNA. Repeated copying of a piece of DNA. In amplification there is an increase in the number of copies of any particular piece of DNA. Gene amplification plays a role in cancer cells. A tumor cell amplifies, or copies, DNA segments as a result of cell signals and sometimes environmental events. Amplification can occur in vivo (in the living individual) or in vitro (literally "in glass", or in a plastic vessel in the laboratory).
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The process of making larger, as in increasing an auditory or visual stimulus to enhance its perception. [L. amplificatio, an enlarging]
- genetic a. a process for producing an increase in pertinent genetic material, particularly for increasing the proportion of plasmid DNA to that of bacterial DNA. Includes the production of extrachromosomal copies of the genes for RNA. This process is usually seen in malignant cells in humans.
- linear a. a hearing aid circuit in which all frequencies receive equivalent a..

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am·pli·fi·ca·tion .am-plə-fə-'kā-shən n
1) an act, example, or product of amplifying
2) a usu. massive replication of genetic material and esp. of a gene or DNA sequence (as in a polymerase chain reaction)

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am·pli·fi·ca·tion (am″plĭ-fĭ-kaґshən) [L. amplificatio] the act or result of increasing in number, size, power, or other variable, such as the increase of an auditory or visual stimulus as a means of improving its perception.

Medical dictionary. 2011.

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  • amplification — [ ɑ̃plifikasjɔ̃ ] n. f. • XIVe; lat. amplificatio 1 ♦ Vx Agrandissement, accroissement. ♢ (1801) Opt. Grossissement. Techn. Opération consistant à accroître une amplitude ou une puissance à l aide d un amplificateur; valeur de cet accroissement… …   Encyclopédie Universelle

  • Amplification — may refer to:* The operation of an amplifier, a natural or artificial device intended to make a signal stronger. * Amplification (rhetoric), a figure of speech that adds importance to increase its rhetorical effect. * Amplification (psychology)… …   Wikipedia

  • amplification — Amplification. s. f. v. Figure de Rhetorique par laquelle l orateur amplifie. Il y a trop d amplification dans ce discours. On appelle aussi Amplification, Le discours entier qui est amplifié sur un sujet qu on a entrepris de traiter. Faire une… …   Dictionnaire de l'Académie française

  • Amplification — Am pli*fi*ca tion, n. [L. amplificatio.] 1. The act of amplifying or enlarging in dimensions; enlargement; extension. [1913 Webster] 2. (Rhet.) The enlarging of a simple statement by particularity of description, the use of epithets, etc., for… …   The Collaborative International Dictionary of English

  • amplification — AMPLIFICATION. s. f. Terme de Rhétorique. Discours par lequel on étend le sujet qu on traite. Il y a trop d amplification dans ce discours. [b]f♛/b] On appelle dans les Colléges, Amplification, Le discours que les écoliers font sur un sujet qu on …   Dictionnaire de l'Académie Française 1798

  • amplification — amplification. См. амплификация. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Amplification — ist die rhetorische Erweiterung eines Gedankens, in dem die Bestandtheile desselben entwickelt werden, entweder in der beschreibenden Manier durch die ins Einzelne gehende Aufführung der Merkmale, oder der Gedanke wird durch Gleichnisse,… …   Herders Conversations-Lexikon

  • amplification — I noun accession, accretion, accrual, accumulation, advance, advancement, aggrandizement, aggravation, augmentation, broadening, clarification, deepening, development, dilation, elaboration, enhancement, enlargement, expansion, explanation,… …   Law dictionary

  • amplification — (n.) 1540s, enlargement, from L. amplificationem (nom. amplificatio) a widening, extending, noun of action from pp. stem of amplificare (see AMPLIFY (Cf. amplify)). Electronics sense is from 1915 …   Etymology dictionary

  • amplification — [n] increase in size or effect addition, augmentation, boost, boosting, buildup, deepening, development, elaboration, enlargement, exaggeration, expansion, expatiation, extension, fleshing out, heightening, intensification, lengthening,… …   New thesaurus

  • amplification — [am΄plə fi kā′shən] n. 1. an amplifying or being amplified 2. matter, details, etc. added to amplify a statement, report, etc. 3. a statement, etc. with something added …   English World dictionary

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