Hemophilia A
Classic hemophilia due to profound deficiency of factor VIII in the blood, which is necessary for normal clotting. The hemophilia A gene is on the X chromosome, so females carry the gene. Each son of a female carrier stands a 50 percent chance of receiving the gene and having hemophilia. Treatment is by blood products that introduce clotting factor and replace lost blood. However, use of contaminated blood products exposed many people with hemophilia to HIV infection in the 1980s. Hemophilia A has affected the Russian royal house and other descendants of Queen Victoria.

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hemophilia A n hemophilia caused by the absence of factor VIII from the blood

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the most common type of hemophilia, an X-linked recessive condition caused by mutation in the coagulation factor VIII gene (F8, locus: Xq28) that results in deficiency of the factor. Called also classical h.

Medical dictionary. 2011.

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  • hemophilia A — hemophilia A. См. гемофилия А. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • hemophilia A — noun hemophilia caused by a congenital deficiency of factor VIII; occurs almost exclusively in men • Syn: ↑haemophilia A, ↑classical hemophilia, ↑classical haemophilia • Hypernyms: ↑hemophilia, ↑haemophilia, ↑bleeder s disease …   Useful english dictionary

  • Hemophilia B — Hemophilia due to deficiency of coagulation factor IX in the blood which results in prolonged oozing after minor and major injuries, tooth extractions, or surgery. There is renewed bleeding after the initial bleeding has stopped. The gene for… …   Medical dictionary

  • Hemophilia — A set of inherited bleeding disorders in which the ability of blood to clot is impaired. * * * An inherited disorder of blood coagulation characterized by a permanent tendency to hemorrhages, spontaneous or traumatic, because of a defect in the… …   Medical dictionary

  • hemophilia — /hee meuh fil ee euh, feel yeuh, hem euh /, n. any of several X linked genetic disorders, symptomatic chiefly in males, in which excessive bleeding occurs owing to the absence or abnormality of a clotting factor in the blood. [1850 55; < NL; see… …   Universalium

  • hemophilia — noun congenital tendency to uncontrolled bleeding; usually affects males and is transmitted from mother to son • Syn: ↑haemophilia, ↑bleeder s disease • Derivationally related forms: ↑haemophilic (for: ↑haemophilia) …   Useful english dictionary

  • hemophilia — Synonyms and related words: Christmas disease, Hand Schuller Christian disease, Hartnup disease, Letterer Siwe syndrome, Werdnig Hoffmann disease, achromatic vision, acute leukemia, albinism, anemia, angiohemophilia, aplastic anemia, chronic… …   Moby Thesaurus

  • hemophilia B — noun a clotting disorder similar to hemophilia A but caused by a congenital deficiency of factor IX • Syn: ↑haemophilia B, ↑Christmas disease • Hypernyms: ↑hemophilia, ↑haemophilia, ↑bleeder s disease …   Useful english dictionary

  • A.I.D.S. — Acquired Immune Deficiency Syndrome, auch Acquired immunodeficiency syndrome (englisch für „erworbenes Immundefektsyndrom“), zumeist abgekürzt als AIDS oder Aids benannt, bezeichnet eine spezifische Kombination von Symptomen, die beim Menschen in …   Deutsch Wikipedia

  • Hemophilia — Hem o*phil i*a (h[=e] m[.a]*f[i^]l [i^]*[.a] or h[e^]m [.a]*f[i^]l [i^]*[.a]), n. [NL., fr. Gr. a i^ma, blood + filei^n to love.] (Med.) A condition characterized by a tendency to profuse and uncontrollable hemorrhage from the slightest wounds;… …   The Collaborative International Dictionary of English

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