Hemophilia B
Hemophilia due to deficiency of coagulation factor IX in the blood which results in prolonged oozing after minor and major injuries, tooth extractions, or surgery. There is renewed bleeding after the initial bleeding has stopped. The gene for hemophilia B gene is on the X chromosome, so males are affected and females carry the gene. About 10% of carrier females are at risk for bleeding. Each son of a female carrier stands a 50 percent chance of receiving the gene and having hemophilia B. Treatment is by blood products that introduce clotting factor IX and replace lost blood. Hemophilia B is also called Christmas disease (so-named for the first patient studied in detail with the disease).

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hemophilia B n CHRISTMAS DISEASE

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an X-linked recessive condition, clinically indistinguishable from hemophilia A, caused by mutation in the coagulation factor IX gene (F9, locus: Xq27.1-q27.2) that results in deficiency of the factor. Called also Christmas disease.

Medical dictionary. 2011.

Look at other dictionaries:

  • hemophilia B — hemophilia B. См. гемофилия В. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • hemophilia B — noun a clotting disorder similar to hemophilia A but caused by a congenital deficiency of factor IX • Syn: ↑haemophilia B, ↑Christmas disease • Hypernyms: ↑hemophilia, ↑haemophilia, ↑bleeder s disease …   Useful english dictionary

  • hemophilia B Leyden — a transient condition in which there is a deficiency of coagulation factor IX, the bleeding tendency abating after puberty, caused by point mutations in the promoter region of the F9 gene …   Medical dictionary

  • hemophilia — /hee meuh fil ee euh, feel yeuh, hem euh /, n. any of several X linked genetic disorders, symptomatic chiefly in males, in which excessive bleeding occurs owing to the absence or abnormality of a clotting factor in the blood. [1850 55; < NL; see… …   Universalium

  • hemophilia — noun congenital tendency to uncontrolled bleeding; usually affects males and is transmitted from mother to son • Syn: ↑haemophilia, ↑bleeder s disease • Derivationally related forms: ↑haemophilic (for: ↑haemophilia) …   Useful english dictionary

  • Hemophilia — A set of inherited bleeding disorders in which the ability of blood to clot is impaired. * * * An inherited disorder of blood coagulation characterized by a permanent tendency to hemorrhages, spontaneous or traumatic, because of a defect in the… …   Medical dictionary

  • hemophilia — Synonyms and related words: Christmas disease, Hand Schuller Christian disease, Hartnup disease, Letterer Siwe syndrome, Werdnig Hoffmann disease, achromatic vision, acute leukemia, albinism, anemia, angiohemophilia, aplastic anemia, chronic… …   Moby Thesaurus

  • Haemophilia B — Classification and external resources ICD 10 D67 ICD 9 286.1 OM …   Wikipedia

  • haemophilia B — noun a clotting disorder similar to hemophilia A but caused by a congenital deficiency of factor IX • Syn: ↑hemophilia B, ↑Christmas disease • Hypernyms: ↑hemophilia, ↑haemophilia, ↑bleeder s disease …   Useful english dictionary

  • Гемофилия B — МКБ 10 D67.67. МКБ 9 286.1286.1 OMIM …   Википедия

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