- Abbreviation for the disease called hereditary hemorrhagic telangiectasia and the gene that causes it, a genetic disease of blood vessels with dilatation (widening) of capillaries and small arteries (arterioles) producing characteristic small red spots (called telangiectases) in the skin and mucous membranes, particularly in the nose and gastrointestinal tract. These spots are fragile and prone to bleed. Recurrent nosebleeds and chronic gastrointestinal bleeding are the usual major problems. Other organs may have the spots and bleed with abnormal ease. Hence, the name "hemorrhagic." Hereditary hemorrhagic telangiectasia (HHT) is inherited as an autosomal dominant disorder. The HHT gene is located on a nonsex (autosomal) chromosome and one copy of this gene is sufficient to cause the disease. The HHT gene has been mapped to chromosome 9 and is band 9q34.1. HHT is also known as Osler-Rendu-Weber and Rendu- Osler-Weber disease or syndrome. Although his name was never given to the disorder, it was first described in 1865 by the British physician Benjamin Guy Babbington (who also invented the laryngoscope).
* * *head halter traction; hereditary hemorrhagic telangiectasia; heterotopic heart transplantation; homoharringtonine; hydroxyheptadecatrienoic acid
* * *hydroxyheptadecatrienoic acid.
Medical dictionary. 2011.