procollagen

procollagen
Soluble precursor of collagen formed by fibroblasts and other cells in the process of collagen synthesis; unstable type III p. is associated with Ehlers-Danlos syndrome type IV.
- p. aminoproteinase an extracellular enzyme that participates in the processing of collagen, removing the extension peptide at the amino-terminal end of p..
- p. carboxyproteinase an extracellular enzyme that participates in the processing of collagen, removing the extension peptide at the carboxy-terminal end of p..

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pro·col·la·gen -'käl-ə-jən n a molecular precursor of collagen

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pro·col·la·gen (pro-kolґə-jən) the precursor molecule of collagen, synthesized in the fibroblast, osteoblast, etc., and cleaved to form collagen extracellularly.

Medical dictionary. 2011.

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  • Procollagen-proline dioxygenase — In enzymology, a procollagen proline dioxygenase (EC number|1.14.11.2) is an enzyme that catalyzes the chemical reaction:procollagen L proline + 2 oxoglutarate + O2 ightleftharpoons procollagen trans 4 hydroxy L proline + succinate + CO2The 3… …   Wikipedia

  • Procollagen-proline 3-dioxygenase — In enzymology, a procollagen proline 3 dioxygenase (EC number|1.14.11.7) is an enzyme that catalyzes the chemical reaction:procollagen L proline + 2 oxoglutarate + O2 ightleftharpoons procollagen trans 3 hydroxy L proline + succinate + CO2The 3… …   Wikipedia

  • Procollagen galactosyltransferase — In enzymology, a procollagen galactosyltransferase (EC number|2.4.1.50) is an enzyme that catalyzes the chemical reaction:UDP galactose + procollagen 5 hydroxy L lysine ightleftharpoons UDP + procollagen 5 (D galactosyloxy) L lysineThus, the two… …   Wikipedia

  • Procollagen glucosyltransferase — In enzymology, a procollagen glucosyltransferase (EC number|2.4.1.66) is an enzyme that catalyzes the chemical reaction:UDP glucose + 5 (D galactosyloxy) L lysine procollagen ightleftharpoons UDP + 1,2 D glucosyl 5 D (galactosyloxy) L lysine… …   Wikipedia

  • procollagen peptidase — pro·col·la·gen pep·ti·dase (pro kolґə jən pepґtĭ dās) an endopeptidase that catalyzes the cleavage of specific terminal segments from procollagen chains, specifically used to denote procollagen N endopeptidase (q.v.) and… …   Medical dictionary

  • Procollagen peptidase — protein Name=procollagen (type III) N endopeptidase caption= width= HGNCid=8740 Symbol=PCOLN3 AltSymbols=PRSM1 EntrezGene=5119 OMIM=164010 RefSeq=NM 002768 UniProt=Q9HD42 PDB= ECnumber=3.4.24.14 Chromosome=16 Arm=q Band=24.3… …   Wikipedia

  • procollagen C-endopeptidase — pro·col·la·gen C en·do·pep·ti·dase (pro kolґə jən en″do pepґtĭ dās) [EC 3.4.24.19] an extracellular endopeptidase that catalyzes the cleavage of the C terminal extension from procollagen, a step in the synthesis of… …   Medical dictionary

  • procollagen N-endopeptidase — pro·col·la·gen N en·do·pep·ti·dase (pro kolґə jən en″do pepґtĭ dās) [EC 3.4.24.14] an extracellular endopeptidase that catalyzes the cleavage of the N terminal extension from procollagen, a step in the synthesis of… …   Medical dictionary

  • procollagen peptidases — The proteases that remove the terminal extension peptides of procollagen; deficiency of these enzymes leads to dermatosparaxis or Ehlers Danlos syndrome …   Dictionary of molecular biology

  • procollagen C-proteinase — pro·col·la·gen C pro·tein·ase (pro kolґə jən proґtēn ās) procollagen C endopeptidase …   Medical dictionary

  • procollagen N-proteinase — pro·col·la·gen N pro·tein·ase (pro kolґə jən proґtēn ās) procollagen N endopeptidase …   Medical dictionary

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