proenzyme

proenzyme
The precursor of an enzyme, requiring some change (usually the hydrolysis of an inhibiting fragment that masks an active grouping) to render it active; e.g., pepsinogen, trypsinogen, profibrolysin. SYN: zymogen.

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pro·en·zyme (')prō-'en-.zīm n ZYMOGEN

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n.
the inactive form in which certain enzymes (e.g. digestive enzymes) are originally produced and secreted. The existence of this inactive form prevents the enzyme from breaking down the cells in which it was made. Once the proenzyme has been secreted it is converted to the active form.

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pro·en·zyme (pro-enґzīm) an inactive precursor that can be converted to the active enzyme. Proenzymes, containing extra-long polypeptide chains that block activity, are activated by acid or enzymatic hydrolysis to remove the inhibiting portion.

Medical dictionary. 2011.

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  • proenzyme — ● proenzyme nom féminin Substance protéinique inactive, donnant naissance, sous l influence d un agent activateur (ion hydrogène ou métallique), à une enzyme active. proenzyme [pʀoɑ̃zim] n. m. ÉTYM. 1904, Rev. gén. des sc., no 12, p. 597; de pro …   Encyclopédie Universelle

  • proenzyme — proenzyme. См. профермент. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • proenzyme — [prō en′zīm΄] n. [ PRO 1 + ENZYME] ZYMOGEN …   English World dictionary

  • Proenzyme — Une proenzyme ou zymogène est un précurseur protéique d une enzyme, c est à dire un composé protidique inactif, dépourvu d activité enzymatique, mais qui peut donner après activation une enzyme active[1]. L intérêt pour l organisme est de pouvoir …   Wikipédia en Français

  • proenzyme — zymogen; n. the inactive form in which certain enzymes (e.g. digestive enzymes) are originally produced and secreted. The existence of this inactive form prevents the enzyme from breaking down the cells in which it was made. Once the proenzyme… …   The new mediacal dictionary

  • proenzyme — noun Etymology: International Scientific Vocabulary Date: circa 1900 zymogen …   New Collegiate Dictionary

  • proenzyme — /proh en zuym/, n. Biochem. any of a group of proteins that are converted to active enzymes by partial breakdown, as by the action of an acid or other enzyme. Also called zymogen. [1895 1900; PRO 1 + ENZYME] * * * …   Universalium

  • proenzyme — noun Any inactive precursor of an enzyme that is converted to an enzyme by proteolysis; a zymogen …   Wiktionary

  • proenzyme — n. zymogen, protein that becomes an enzyme under certain conditions (Biochemistry) …   English contemporary dictionary

  • proenzyme — pro·enzyme …   English syllables

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