progabide

progabide
An anticonvulsant that is a lipid-soluble derivative of the amidated form of γ-aminobutyric acid (GABAmide) that, unlike γ-aminobutyric acid (GABA) itself, is able to cross the blood-brain barrier. Once inside the brain the drug is converted to several metabolites, some of which are active forms of GABA or related compounds that act on GABA receptors to increase inhibition in the brain.

Medical dictionary. 2011.

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  • Progabide — drugbox IUPAC name = 4 [(4 chlorophenyl) (5 fluoro 2 hydroxy phenyl) methylidene] aminobutanamide CAS number = 62666 20 0 ATC prefix = N03 ATC suffix = AG05 ATC supplemental = PubChem = 5361323 DrugBank = APRD00072 C = 17 | H = 16 | Cl = 1 | F =… …   Wikipedia

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