promegaloblast

promegaloblast
The earliest of four maturation stages of the megaloblast. See erythroblast. SYN: pernicious anemia type rubriblast.

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pro·meg·a·lo·blast (')prō-'meg-ə-lō-.blast n a cell that produces megaloblasts and is possibly equivalent to a hemocytoblast called also erythrogone

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pro·meg·a·lo·blast (pro-megґə-lo-blast) the earliest developmental form in the abnormal red cell maturation sequence occurring in vitamin B12 and folic acid deficiencies; it corresponds to the pronormoblast, but differs from it by its larger size, abundant basophilic cytoplasm, and reticulated, unclumped nuclear chromatin. Several nucleoli are usually present.

Medical dictionary. 2011.

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  • Promegaloblast — Pro|megalo|blạst [↑pro... u. ↑Megaloblast] m; en, en: Vorstufe des Megaloblasten in der Erythropoese mit auffallend großem, leicht ovalem Kern …   Das Wörterbuch medizinischer Fachausdrücke

  • promegaloblast — pro·megaloblast …   English syllables

  • promegaloblast — (ˈ)prō+ noun Etymology: pro (I) + megaloblast : a cell that produces megaloblasts and is possibly equivalent to a hemocytoblast …   Useful english dictionary

  • Proerythroblast — A proerythroblast (or rubriblast, or pronormoblast) is the earliest of four stages in development of the normoblast.In histology, it is very difficult to distinguish it from the other blast cells (lymphoblast, myeloblast, monoblast, and… …   Wikipedia

  • megaloblast — A large, nucleated, embryonic type of cell that is a precursor of erythrocytes in an abnormal erythropoietic process observed in pernicious anemia; a megaloblasts four stages of development are as follows: 1) …   Medical dictionary

  • erythroblast — Originally, a term denoting all forms of human red blood cells containing a nucleus, both pathologic ( i.e., megaloblastic) and normal ( e.g., normoblastic). The pathologic or megaloblastic series is observed in pernicious anemia in relapse. The… …   Medical dictionary

  • pronormoblast — The earliest of four stages in development of the normoblast. SEE ALSO: erythroblast. SYN: proerythroblast, rubriblast. * * * pro·nor·mo·blast ( )prō nȯr mə .blast n a cell recognized in some theories of erythropoiesis that arises from a… …   Medical dictionary

  • rubriblast — SYN: pronormoblast. [L. ruber, red, + G. blastos, germ] pernicious anemia type r. SYN: promegaloblast. See erythroblast. * * * ru·bri·blast rü bri .blast n PRONORMOBLAST …   Medical dictionary

  • erythrogone — eryth·ro·gone i rith rə .gōn n PROMEGALOBLAST …   Medical dictionary

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